PRIN 2017 - Actlife: is active life style enough for health and wellbeing?

Starting date
August 29, 2019
Duration (months)
Neurosciences, Biomedicine and Movement Sciences
Managers or local contacts
Schena Federico

Sedentary lifestyles in modern obesogenic society produce several dysfunctions that cause chronic diseases and this phenomen is becoming a major public health problem. Regular physical activity has a profound effect on the expression of the potentials of human resilience, resulting in a decreased risk of chronic diseases.
The identification of the bioactive molecules and biological mechanisms that are candidates for exercise-induced health benefits through biological pathways that are largely different from those targeted by common drugs, is highly relevant, since it might help to improve our knowledge of the pathophysiology of the chronic diseases in the sedentary population as well as to maximize the efficacy of physical activity interventions by implementing the best possible exercise dosage. For this purpose, the first aim of this project will be to identify the bioactive molecules and functional mechanisms that are candidates for exercise-induced health benefits. Moreover, in the view of more reliable, ecological and tailored approaches to counteract the problem of sedentary lifestyle, the second aim of this project will be to evaluate the effectiveness of an ecological exercise intervention in comparison to a traditional exercise intervention.


Funds: assigned and managed by the department
Syllabus: PRIN

Project participants

Anna Pedrinolla
Professor from another university
Federico Schena
Full Professor
Massimo Venturelli
Associate Professor
Francesca Vitali
Temporary Assistant Professor

Collaboratori esterni

Fabio Naro
Università degli Studi di Roma
Pasqualina Buono
Università degli Studi di Napoli
Prisco Mirandola
Università degli Studi di Parma
Antonio Paoli
Università degli Studi di Padova
Corrado Lupo
Università degli Studi di Torino
Research areas involved in the project


Research facilities