Bionformatica applicata alla genomica (2020/2021)

Course code
cod wi: DT000132
Name of lecturer
Maria Romanelli
Coordinator
Maria Romanelli
Number of ECTS credits allocated
2
Academic sector
BIO/13 - EXPERIMENTAL BIOLOGY
Language of instruction
Italian
Location
VERONA
Period
A.A. 20/21 dottorato dal Oct 1, 2020 al Sep 30, 2021.

Lesson timetable

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Learning outcomes

The course aims to introduce the students to the use of Biomedical databases accessible via the computer network. Teaching is aimed at enabling the student to acquire knowledge of the information accessible from the major biological and genetic databases and to develop the ability to use genomic analysis tools in the study of human diseases

Syllabus

During the practical exercises, the following computational tools for querying the major databases will be used: GeneBank, Genecards, SwissProt, CDD (Conserved Domain Database), and OMIM (Online Mendelian Inheritance in Man). The human genome sequences will be analyzed using alignment algorithms such as BLAST (Basic Local Alignment Search Tool) and FASTA; research strategies based on the alignment programs will be applied to genomic sequence analysis; programs accessible by the server ExPASy (Expert Protein Analysis System) Bioinformatic resource portal will be used for protein analysis.

Reference books
Author Title Publisher Year ISBN Note
Citterich et al. Fondamenti di bioinformatica Zanichelli 2018 978-88-08-62112-2

Assessment methods and criteria


Active participation in all the meetings is mandatory to obtain a positive evaluation.

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