Fusion complexes and CD4-independent Env for the induction of broad spectrum neutralizing antibodies against HIV-1
Anno:
2011
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
Elettronico
Referee:
No
Nome rivista:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
ISSN Rivista:
1525-4135
N° Volume:
56
Editore:
Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
Intervallo pagine:
65-65
Parole chiave:
HIV-1neutralizing antibodyAIDS
Breve descrizione dei contenuti:
Broad spectrum neutralizing antibodies against HIV-1 are essential for the development of a humoral anti-AIDS vaccine. We used fusion complexes and CD4-independent gp120 as new immunogens to induce neutralizing antibodies blocking the infectivity of different primary isolates of HIV-1.