Davide Papola

Foto,  May 7, 2019
Position
Research Scholarship Holders
Sections
Section of Psychiatry and Clinical Psychology
Academic sector
MED/25 - PSYCHIATRY
Telephone
+39 045 812 4065
E-mail
davide|papola*univr|it <== Replace | with . and * with @ to have the right email address.
Curriculum

Titolo assegno di ricerca ADR 3791/2021: "Valutazione della tollerabilità ed efficacia della vortioxetina versus SSRIs in pazienti anziani con depressione: trial di superiorità, randomizzato, multicentrico, open-label a gruppi paralleli" progetto AIFA Studio VESPA.
Referente scientifico: PROF. CORRADO BARBUI

I am a psychiatrist with a PhD in Clinical Epidemiology at the University of Verona (UNIVR) (Verona, Italy).
My research activities concern: global mental health; evaluation of efficacy and acceptability of psychotropic drugs and psychotherapies; evaluation and improvement of the production of scientific evidence through to its application in clinical practice (translational research). A major output of this research is the production of guidelines and indications for clinical policies consistent with the precepts of Evidence-Based Medicine and the shared decision-making process. My expertise lies in the design and creation of systematic reviews, meta-analyses, and clinical guidelines.
I have collaborated with Professor Corrado Barbui since 2011, working on the efficacy and acceptability of antidepressants and psychotropic agents in general. Professor Barbui was my Research Advisor when I discussed my thesis to become a physician (2012), a psychiatrist (2018), and a PhD (2021). In 2017 I spent 6 months at McMaster University (Ontario – Canada) supervised by Professor Gordon Guyatt to acquire knowledge in research methodology and the GRADE method in particular. Having acquired sound training in the GRADE method, I was among the first researchers to apply it in an innovative type of review, termed “umbrella review”, developed to assess the credibility of evidence generated by meta-analyses. In 2019 I spent 6 months at the Vrije Universiteit (VU) (Amsterdam – the Netherlands) under the supervision of Professor Pim Cuijpers with whom I started a prolific collaboration on psychotherapy research. During my stay at VU I created a database that contains the data from all of the randomized controlled trials (RCTs) on the efficacy and acceptability of diverse types of psychotherapy for anxiety disorders. Since 2016 I have been actively involved in global mental health as a member of the Cochrane Global Mental Health (GMH) Network established in 2017 by Cochrane and based at the World Health Organization Collaborating Centre for Research and Training in Mental Health and Service Evaluation (WHO CC) at UNIVR, where I currently work. Through the GMH network, in 2019 I started collaboration with Professor Vikram Patel, with whom I co-authored a recent Lancet Psychiatry paper.
To date, I have published 37 journal articles, 33 of which have appeared in international peer-reviewed journals, including papers in the Lancet Psychiatry, the Lancet Global Health, the BMJ, BMC Medicine, and the Cochrane Library. I am actively involved in several international ongoing projects, including projects in collaboration with: the WHO; the European Union (Horizon 2020 scheme); McMaster University (Canada); Vrije Universiteit (Holland); the Italian Medicine Agency (Agenzia Italiana del Farmaco – AIFA), the Italian National Health Institute (Istituto Superiore di Sanità - ISS), and the Italian National Centre for Clinical Excellence (Centro Nazionale per l’Eccellenza Clinca – CNEC).

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Il Dott. Papola si è laureato con lode in Medicina e Chirurgia nel 2012 presso L’Università degli Studi di Verona sotto la supervisione del Prof. Corrado Barbui, presentando la tesi: "Efficacia e tollerabilità della paroxetina nella depressione maggiore unipolare: revisione sistematica e metanalisi Cochrane delle sperimentazioni randomizzate", pubblicata sulla Cochrane Library.
Nel 2017 ha trascorso un periodo presso la McMaster University (Canada) per perfezionare lo studio della metodologia applicata alla ricerca epidemiologica clinica, sotto il tutoraggio del Prof. Gordon Guyatt. Nel 2018 ha conseguito la specializzazione con lode in Psichiatria presso l'Università di Verona con la tesi: "Focused psychosocial interventions for children in low-resource humanitarian settings: a systematic review and individual participant data meta-analysis“, pubblicata sulla rivista "Lancet Global Health”. Nel 2019 ha trascorso 6 mesi presso la Vrije Universiteit di Amsterdam sotto la supervisione del Prof. Pim Cuijpers, per approfondire lo studio dell’efficacia comparata dei diversi tipi di psicoterapie per la cura dei disturbi d’ansia. In giugno 2021 ha conseguito un dottorato di ricerca in epidemiologia clinica discutendo la tesi: "The RE-DEFINE project and the effectiveness of SH+ in preventing mental disorders in refugees and asylum seekers resettled in europe: a multicentre randomised controlled trial".
Ad oggi il Dott. Papola è assegnista di ricerca presso l'Università di Verona, occupandosi dei seguenti ambiti di ricerca: valutazione dell'efficacia e tollerabilità degli psicofarmaci, trattamento farmacologico di disturbi ansiosi e depressivi, sviluppo di linee guida seguendo la cornice metodologica dell'Evidence-Based Medicine (EBM).
Il Dott. Papola è attualmente è coinvolto in progetti di ricerca in collaborazione con: Vreij Universiteit - Amsterdam (VU), Istituto superiore di Sanità (ISS), Organizzazione Mondiale della Sanità (OMS), Agenzia Italiana del Farmaco (AIFA).

Evidence Based Medicine; Global Mental Health; Research Methodology; Implementation science; Pharmacoepidemiology; Epidemiology of Psychotherapeutic Interventions.

Modules

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Research groups

CLINICAL PSYCHOPHARMACOLOGY AND DRUG-EPIDEMIOLOGY
The main research interests of the Unit include: (a) pharmaco-epidemiology, oriented to describe the beneficial and harmful effects of psychotropic drugs in ordinary practice; (b) randomized controlled trials, oriented to assess the efficacy and tolerability profile of psychotropic drugs in experimental conditions; (c) systematic reviews, oriented to summarize clinical trial findings using meta-analytical techniques.



Organisation

Department facilities