European Vaccines and Microbicides Enterprise (EUROPRISE)

Starting date
January 1, 2007
Duration (months)
60
Managers or local contacts
Zipeto Donato
Keyword
anticorpi, HIV, vaccino

Studio di nuovi immunogeni per lo sviluppo di anticorpi monoclonali ad ampio spettro contro HIV-1 nell'ambito del progetto di ricerca dell'Unione Europea "EUROPRISE"

Sponsors:

Unione Europea
Funds: assigned and managed by the department
Syllabus: EUROPA - Progetti Europei

Project participants

Dalila Astone
Andrea Matucci
Pierpaolo Racchiolli
Paola Rossolillo
Serena Ziglio
Donato Zipeto
Associate Professor
Publications
Title Authors Year
Fusion complexes and CD4-independent Env for the induction of broad spectrum neutralizing antibodies against HIV-1 Astone, Dalila; Rossolillo, Paola; Matucci, Andrea; Racchiolli, Pierpaolo; Cara, A.; Zipeto, Donato 2011
HLA-C associates with Env and Increases HIV-1 infectivity Turci, Marco; Racchiolli, Pierpaolo; Ziglio, Serena; Astone, Dalila; Blanco, A.; Zipeto, Donato 2011
Fusion complexes and CD4-independene Env for the induction of broad spectrum neutralizing antibodies against HIV-1 Astone, Dalila; Rossolillo, Paola; Matucci, Andrea; Racchiolli, Pierpaolo; Cara, A.; Zipeto, Donato 2010
HLA-C associates with Env and increases HIV-1 infectivity Turci, Marco; Racchiolli, Pierpaolo; Ziglio, Serena; Astone, Dalila; Blanco, A.; Zipeto, Donato 2010
HLA-C increases HIV-1 infectivity by interacting with the envelope glycoprotein gp120 Blanco, A.; Ziglio, Serena; Racchiolli, Pierpaolo; Astone, Dalila; Turci, Marco; Zipeto, Donato 2010
HLA-C increases human immunodeficiency type 1 (HIV-1) infectivity by interacting with the envelope glycoprotein gp120/41. Turci, Marco; Racchiolli, Pierpaolo; Astone, Dalila; Zipeto, Donato 2010
HLA-C is necessary for optimal HIV-1 infection of human peripheral blood CD4 lymphocytes Baroni, M.; Matucci, Andrea; Scarlatti, G.; Soprana, E.; Rossolillo, Paola; Lopalco, L.; Zipeto, Donato; Siccardi, A. G. 2010
Influenza - Prous Science Integrity Zipeto, Donato 2010
Broad spectrum neutralizing antibodies against HIV-1 elicited by immunizing with fusion complexes and CD4-independent gp120/41s. Astone, Dalila; Rossolillo, Paola; Matucci, Andrea; Racchiolli, Pierpaolo; Ruggiero, A.; Zipeto, Donato 2009
HLA-C presence increases human immunodeficiency type 1 (HIV-1) infectivity by interacting with the envelope glycoprotein gp120/41 Turci, Marco; Racchiolli, Pierpaolo; Astone, Dalila; Ruggiero, Alessandra; Antonio, Siccardi; Alberto, Beretta; Zipeto, Donato 2009
New immunogens for the induction of broad spectrum neutralizing antibodies against human immunodeficiency virus type 1 (HIV-1) Astone, Dalila; Rossolillo, Paola; Matucci, Andrea; Racchiolli, Pierpaolo; Ruggieri, A.; Zipeto, Donato 2009
Presence and role of HLA-C in HIV-1 infection Matucci, Andrea; Rossolillo, Paola; Turci, Marco; Racchiolli, Pierpaolo; Siccardi, A. G.; Beretta, A.; Zipeto, Donato 2009
Unsung hero Robert C. Gallo Abbadessa, G; Accolla, R; Aiuti, F; Albini, A; Aldovini, A; Alfano, M; Antonelli, G; Bartholomew, C; Bentwich, Z; Bertazzoni, Umberto; Berzofsky, Ja; Biberfeld, P; Boeri, E; Buonaguro, L; Buonaguro, Fm; Bukrinsky, M; Burny, A; Caruso, A; Cassol, S; Chandra, P; Ceccherini Nelli, L; Chieco Bianchi, L; Clerici, M; Colombini Hatch, S; de Giuli Morghen, C; de Maria, A; de Rossi, A; Dierich, M; Della Favera, R; Dolei, A; Douek, D; Erfle, V; Felber, B; Fiorentini, S; Franchini, G; Gershoni, Jm; Gotch, F; Green, P; Greene, Wc; Hall, W; Haseltine, W; Jacobson, S; Kallings, Lo; Kalyanaraman, Vs; Katinger, H; Khalili, K; Klein, G; Klein, E; Klotman, M; Klotman, P; Kotler, M; Kurth, R; Lafeuillade, A; La Placa, M; Lewis, J; Lillo, F; Lisziewicz, J; Lomonico, A; Lopalco, L; Lori, F; Lusso, P; Macchi, B; Malim, M; Margolis, L; Markham, Pd; Mcclure, M; Miller, N; Mingari, Mc; Moretta, L; Noonan, D; O'Brien, S; Okamoto, T; Pal, R; Palese, P; Panet, A; Pantaleo, G; Pavlakis, G; Pistello, M; Plotkin, S; Poli, G; Pomerantz, R; Radaelli, A; Robertguroff, M; Roederer, M; Sarngadharan, Mg; Schols, D; Secchiero, P; Shearer, G; Siccardi, A; Stevenson, M; Svoboda, J; Tartaglia, J; Torelli, G; Tornesello, Ml; Tschachler, E; Vaccarezza, M; Vallbracht, A; van Lunzen, J; Varnier, O; Vicenzi, E; von Melchner, H; Witz, I; Zagury, D; Zagury, Jf; Zauli, G; Zipeto, Donato 2009
Broad spectrum neutralizing monoclonal antibodies against HIV-1 elicited by immunizing with fusion complexes Rossolillo, P.; Matucci, Andrea; Racchiolli, P.; Mainetti, L.; Dispinseri, S.; Scarlatti, G.; Zipeto, Donato 2008
Demonstration of the role of HLA-C in HIV-1 infection by siRNA silencing Baroni, M.; DE SANTIS, C.; Soprana, E.; Matucci, Andrea; Rossolillo, P.; Zipeto, Donato; Scarlatti, G.; Siccardi, A. G. 2007
Fusion complexes as immunogens for the induction of broad spectrum neutralizing antibodies against HIV-1 Rossolillo, P.; Matucci, Andrea; Scarlatti, G.; Zipeto, Donato 2007
Fusion efficiency between the HIV-1 envelope and the target cell membrane is enhanced by the presence of HLA-C molecules Matucci, Andrea; Rossolillo, P.; Baroni, M.; Siccardi, A. G.; Zipeto, Donato 2007

Activities

Research facilities