Pubblicazioni

Autori:

Marco Turci, Julie Lodewick, Paola Righi, Angela Polania, Maria Grazia Romanelli, Françoise Bex, Umberto Bertazzoni

Titolo:

HTLV-2B Tax oncoprotein is modified by ubiquitination and sumoylation and displays intracellular localization similar to its homologue HTLV-1 Tax.

Anno:

2009

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Nazioni degli autori:

BELGIO; ITALIA

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

Virology

ISSN Rivista:

0042-6822

N° Volume:

386

Serie:

0042-6822

Numero o Fascicolo:

1

Intervallo pagine:

6-11

Codice PMID:

19195675

Parole chiave:

HTLV Tax CREB NF-κB Ubiquitination Sumoylation Nuclear bodies

Note:

HTLV-1 is more pathogenic than HTLV-2B. The difference is generally attributed to the properties of their individual transactivating Tax proteins. By using internal Flag-6His tagged Tax-1 and Tax-2B, which display transcriptional activities comparable to the untagged proteins and can be recognized by a single anti-Flag antibody, we demonstrate that Tax-2B is modified by ubiquitination and sumoylation. In addition, Tax2B is distributed in punctuate nuclear structures that include the RelA subunit of NF-kappaB, as has been previously demonstrated for Tax-1.

Id prodotto:

48907

Handle IRIS:

11562/-327503

depositato il:

1 marzo 2009

ultima modifica:

1 marzo 2009

Citazione bibliografica:

Marco Turci, Julie Lodewick, Paola Righi, Angela Polania, Maria Grazia Romanelli, Françoise Bex, Umberto Bertazzoni, HTLV-2B Tax oncoprotein is modified by ubiquitination and sumoylation and displays intracellular localization similar to its homologue HTLV-1 Tax. «Virology» , vol. 386 , n. 1 ,  0042-6822 , 2009 , pp. 6-11

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