Publications

Authors:

Mariotto, S; Bonetti, B; Donato, F; Micheletti, N; Zanoni, T; Moretto, G; Squintani, G

Title:

Ophthalmoparesis mimicking myasthenia gravis as acute manifestation of Hashimoto’s encephalopathy

Year:

2015

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

JOURNAL OF MULTIPLE SCLEROSIS

ISSN of journal:

2376-0389

N° Volume:

2

Number or Folder:

134

Page numbers:

1-2

Keyword:

n/a

Short description of contents:

Hashimoto’s encephalopathy is a rare steroid-responsive disorder in which neuropsychological and neurological symptoms are associated with Hashimoto’s thyroiditis. Recently, it has gained attention in the differential diagnosis of encephalopathy of unknown origin, although its pathogenesis is poorly understood. The diagnosis of Hashimoto’s encephalopathy rests upon the association of autoimmune thyroiditis and neurological symptoms after excluding more common diseases, but is a serious challenge in atypical cases. We here present a patient with isolated ocular disorder as presenting and unic feature of Hashimoto’s encephalopathy that resolved with steroids therapy. Brain MRI showed non-specific white matter abnormalities; EEG and an extensive neurophysiological investigation were normal. The diagnosis in this euthyroid patient was supported by the presence of serum anti-thyroid antibodies and the identification in the CSF of anti-dimethylargininase-I and aldehyde reductase-I autoantibodies. The description of atypical cases of this rare but certainly underestimated condition is clinically important and adds relevant information for the clinical practice.

Product ID:

118019

Handle IRIS:

11562/1031102

Last Modified:

November 6, 2022

Bibliographic citation:

Mariotto, S; Bonetti, B; Donato, F; Micheletti, N; Zanoni, T; Moretto, G; Squintani, G, Ophthalmoparesis mimicking myasthenia gravis as acute manifestation of Hashimoto’s encephalopathy «JOURNAL OF MULTIPLE SCLEROSIS» , vol. 2 , n. 134 , 2015 , pp. 1-2

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