Publications

Authors:

Tamburin, Stefano; Park, Susanna B; Schenone, Angelo; Mantovani, Elisa; Hamedani, Mehrnaz; Alberti, Paola; Yildiz-Kabak, Vesile; Kleckner, Ian R; Kolb, Noah; Mazzucchelli, Miryam; Mcneish, Brendan; Argyriou, Andreas A; Cavaletti, Guido; Hoke, Ahmet

Title:

Rehabilitation, exercise, and related non-pharmacological interventions for chemotherapy-induced peripheral neurotoxicity: systematic review and evidence-based recommendations

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

Critical Review in Oncology/Hematology

ISSN of journal:

1040-8428

N° Volume:

171

Number or Folder:

103575

Page numbers:

1-20

Keyword:

Chemotherapy-induced peripheral neurotoxicity (CIPN); evidence-based medicine; exercise; physical therapy; rehabilitation; treatment

Short description of contents:

Pharmacological strategies for chemotherapy-induced peripheral neurotoxicity (CIPN) are very limited. We systematically reviewed data on rehabilitation, exercise, physical therapy, and other physical non-pharmacological interventions and offered evidence-based recommendations for the prevention and treatment of CIPN. A literature search using PubMed, Web of Science and CINAHL was conducted from database inception until May 31st, 2021. 2791 records were title-abstract screened, 71 papers were full-text screened, 41 studies were included, 21 on prevention and 20 on treatment of CIPN. Treatment type, cancer type, chemotherapy compounds were heterogeneous, sample size was small (median: N = 34) and intention-to-treat analysis was lacking in 26/41 reports. Because of the methodological issues of included studies, the reviewed evidence should be considered as preliminary. Exercise, endurance, strength, balance, and sensorimotor training have been studied in low-to-moderate quality studies, while the evidence for other treatments is preliminary/inconclusive. We offer recommendation for the design of future trials on CIPN.

Web page:

https://doi.org/10.1016/j.critrevonc.2021.103575

Product ID:

124044

Handle IRIS:

11562/1054785

Last Modified:

November 17, 2022

Bibliographic citation:

Tamburin, Stefano; Park, Susanna B; Schenone, Angelo; Mantovani, Elisa; Hamedani, Mehrnaz; Alberti, Paola; Yildiz-Kabak, Vesile; Kleckner, Ian R; Kolb, Noah; Mazzucchelli, Miryam; Mcneish, Brendan; Argyriou, Andreas A; Cavaletti, Guido; Hoke, Ahmet, Rehabilitation, exercise, and related non-pharmacological interventions for chemotherapy-induced peripheral neurotoxicity: systematic review and evidence-based recommendations «Critical Review in Oncology/Hematology» , vol. 171 , n. 103575 , 2022 , pp. 1-20

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