Publications

Authors:

Maluta, Tommaso; Lavagnolo, Umberto; Segalla, Lydia; Elena, Nicholas; Bernardi, Paolo; Degl'Innocenti, Daniele; Sbarbati, Andrea; Magnan, Bruno

Title:

Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: an in vivo study

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

EUROPEAN JOURNAL OF HISTOCHEMISTRY

ISSN of journal:

2038-8306

N° Volume:

66

Number or Folder:

3313

Page numbers:

1-7

Keyword:

polymethylmetacrilate; calcium phosphate cement; osteointegration; osteoconduction; biocompatibility; compression; environmental scanning electron microscopy

Short description of contents:

The mixture of polymethylmethacrylate (PMMA) and β-tricalciumphospate (β-TCP) is the most widely used bone graft. Common features of bone cement are the biocompatibility, bioactivity, mechanical stability and ability to fuse with the host's bone tissue. However, there are still few studies that have evaluated these characteristics in vivo. Our study aims to acquire these parameters, using an animal model with functional characteristics similar to those of humans. The analyzed cement is Calcemex®, evaluated both in compact and fluid formulation. The chosen animal models were 5 pigs, treated with femoral and tibial implants of Calcemex® samples. After one year, the pigs were sacrificed and the specimens explanted for morphological, histological, ultrastructural and mechanical evaluations. For both formulations, the investigation highlighted the absence of foreign body reactions in the host, the histological integration with the surrounding tissues and the preservation of mechanical compression resistance.

Web page:

https://doi.org/10.4081/ejh.2022.3313

Product ID:

124694

Handle IRIS:

11562/1056897

Last Modified:

November 15, 2022

Bibliographic citation:

Maluta, Tommaso; Lavagnolo, Umberto; Segalla, Lydia; Elena, Nicholas; Bernardi, Paolo; Degl'Innocenti, Daniele; Sbarbati, Andrea; Magnan, Bruno, Evaluation of biocompatibility, osteointegration and biomechanical properties of the new Calcemex® cement: an in vivo study «EUROPEAN JOURNAL OF HISTOCHEMISTRY» , vol. 66 , n. 3313 , 2022 , pp. 1-7

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo