Publications

Authors:

Dinoto, Alessandro; Sechi, Elia; Ferrari, Sergio; Gajofatto, Alberto; Orlandi, Riccardo; Solla, Paolo; Maccabeo, Alessandra; Maniscalco, Giorgia Teresa; Andreone, Vincenzo; Sartori, Arianna; Manganotti, Paolo; Rasia, Sarah; Capra, Ruggero; Mancinelli, Chiara Rosa; Mariotto, Sara

Title:

Risk of disease relapse following COVID-19 vaccination in patients with AQP4-IgG-positive NMOSD and MOGAD

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

MULTIPLE SCLEROSIS AND RELATED DISORDERS

ISSN of journal:

2211-0348

N° Volume:

58

Number or Folder:

103424

Page numbers:

1-4

Keyword:

AQP4; MOG; MOGAD; NMOSD; SARS-CoV-2; vaccination

Short description of contents:

Post-vaccination disease relapses have been reported in patients with MOGAD and AQP4-IgG+NMOSD. In this retrospective multicenter Italian study we assessed the frequency of relapses after SARS-CoV-2 vaccination. We included 56 cases: MOGAD, 30; AQP4-IgG+NMOSD, 26. Vaccines received were BNT162b2-Pfizer-BioNTech in 42 patients and mRNA-1273-Moderna in 14 patients. Six patients had a history of SARS-CoV-2 infection; two of them experienced a post-infection disease relapse (MOGAD). The frequency of relapses within one month of SARS-CoV-2 vaccination was 4% (1/26) in the AQP4-IgG+NMOSD group and 0% in the MOGAD group. In these patients the potential benefits of vaccination overcome the risk of relapses.

Web page:

https://doi.org/10.1016/j.msard.2021.103424

Product ID:

125111

Handle IRIS:

11562/1058664

Last Modified:

November 15, 2022

Bibliographic citation:

Dinoto, Alessandro; Sechi, Elia; Ferrari, Sergio; Gajofatto, Alberto; Orlandi, Riccardo; Solla, Paolo; Maccabeo, Alessandra; Maniscalco, Giorgia Teresa; Andreone, Vincenzo; Sartori, Arianna; Manganotti, Paolo; Rasia, Sarah; Capra, Ruggero; Mancinelli, Chiara Rosa; Mariotto, Sara, Risk of disease relapse following COVID-19 vaccination in patients with AQP4-IgG-positive NMOSD and MOGAD «MULTIPLE SCLEROSIS AND RELATED DISORDERS» , vol. 58 , n. 103424 , 2022 , pp. 1-4

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