Publications

Authors:

Tagliapietra, Matteo; Turri, Giulia; Bortolotti, Federica; Mansueto, Giancarlo; Monaco, Salvatore

Title:

Ischemic stroke due to sporadic and genetic pulmonary arteriovenous malformations: case report

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

BRAIN CIRCULATION

ISSN of journal:

2394-8108

N° Volume:

8

Number or Folder:

1

Page numbers:

57-60

Keyword:

Arteriovenous malformation; cerebrovascular disorders; computerized tomography angiography; echocardiography; hereditary hemorrhagic; telangiectasia; novel ENG mutation

Short description of contents:

Pulmonary arteriovenous malformations (PAVMs) encompass congenital and genetic vascular anomalies characterized by complex interlacing of arteries and veins connected by fistulas, which allow rapid and continuous extracardiac right-to-left shunting (RLS). Presenting neurologic manifestations of PAVM include brain abscess and stroke, as the consequence of paradoxical embolism. Although rare, PAVM represents an overlooked cause of cryptogenic ischemic stroke in young adults, being misdiagnosed as patent foramen ovale and a preventable trigger of silent cerebral ischemic changes. In the emergency clinical setting, the recommended ischemic stroke workup in patients with RLS should include the influence of postural changes and the effect of Valsalva maneuver on the entity of the RLS on contrast-enhanced transcranial color Doppler ultrasound and the delay in the right inferior pulmonary vein and left heart opacification on contrast-enhanced transthoracic echocardiography. This is in addition to the evaluation of chest X-rays or thoracic computed tomography. We here describe two patients with ischemic stroke due to sporadic and genetic PAVM-associated paradoxical embolism.

Web page:

https://doi.org/10.4103/bc.bc_66_21

Product ID:

125658

Handle IRIS:

11562/1061318

Last Modified:

November 13, 2022

Bibliographic citation:

Tagliapietra, Matteo; Turri, Giulia; Bortolotti, Federica; Mansueto, Giancarlo; Monaco, Salvatore, Ischemic stroke due to sporadic and genetic pulmonary arteriovenous malformations: case report «BRAIN CIRCULATION» , vol. 8 , n. 1 , 2022 , pp. 57-60

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