Publications

Authors:

Lambe, J.; Mcginley, M. P.; Moss, B. P.; Mao-Draayer, Y.; Kassa, R.; Ciotti, J. R.; Mariotto, S.; Kunchok, A.

Title:

Myelin oligodendrocyte glycoprotein-IgG associated disorders (MOGAD) following SARS-CoV-2 infection: A case series

Year:

2022

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

Journal of Neuroimmunology

ISSN of journal:

0165-5728

N° Volume:

370

Number or Folder:

577933

Page numbers:

1-5

Keyword:

COVID-19; MOGAD; Optic neuritis; SARS-CoV-2; Transverse myelitis

Short description of contents:

This case series describes 9 patients diagnosed with myelin oligodendrocyte glycoprotein (MOG)-IgG associated disorder (MOGAD) following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Patients developed neurological symptoms between 4 days and 5 weeks following SARS-CoV-2 infection. Myelitis was observed in 4 patients; 4 presented with optic neuritis; and encephalopathy was observed in 3. Serum MOG-IgG cell-based assay was medium or high positive in each case. The majority of patients had near-complete recovery following acute immunosuppression. This series adds to the growing number of cases of central nervous system demyelination following SARS-CoV-2 infection and highlights a potential role of infection in the immunopathogenesis of MOGAD.

Web page:

https://doi.org/10.1016/j.jneuroim.2022.577933

Product ID:

128121

Handle IRIS:

11562/1072333

Last Modified:

February 23, 2023

Bibliographic citation:

Lambe, J.; Mcginley, M. P.; Moss, B. P.; Mao-Draayer, Y.; Kassa, R.; Ciotti, J. R.; Mariotto, S.; Kunchok, A., Myelin oligodendrocyte glycoprotein-IgG associated disorders (MOGAD) following SARS-CoV-2 infection: A case series «Journal of Neuroimmunology» , vol. 370 , n. 577933 , 2022 , pp. 1-5

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