Pubblicazioni

Autori:

Gecaite-Stonciene, Julija; Hughes, Brian M; Kazukauskiene, Nijole; Bunevicius, Adomas; Burkauskas, Julius; Neverauskas, Julius; Bellani, Marcella; Mickuviene, Narseta

Titolo:

Cortisol response to psychosocial stress, mental distress, fatigue and quality of life in coronary artery disease patients

Anno:

2022

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

SCIENTIFIC REPORTS

ISSN Rivista:

2045-2322

N° Volume:

12

Numero o Fascicolo:

19373

Intervallo pagine:

1-12

Parole chiave:

Hydrocortisone; Quality of Life; Cross-Sectional Studies; Anxiety; Stress, Psychological; Depression; Coronary Artery Disease; Acute Coronary Syndrome

Breve descrizione dei contenuti:

We aimed to explore the relationship between cortisol response to psychosocial stress, mental distress, fatigue and health related quality of life (HRQoL) in individuals with coronary artery disease (CAD) after recent acute coronary syndrome (ACS). A cross-sectional study initially included 113 subjects (88% men, 53 ± 7 years) 1-3 weeks after ACS. Cortisol response was assessed by measuring salivary cortisol during Trier Social Stress Test. Mental distress was measured with Hospital Anxiety and Depression Scale, State-Trait Anxiety Inventory, and Type D Scale-14. Fatigue symptoms were evaluated using Multidimensional Fatigue Inventory 20-items, while HRQoL was assessed with 36-Item Short Form Medical Outcome Questionnaire. After conducting multivariable linear regression analyses, diminished cortisol response sampled after Public speech (T3-T1, + 15 min) was significantly associated with higher anxiety symptoms (β = -0.224; p = 0.035), while diminished cortisol response sampled after preparation time (T2-T1, + 10 min) was significantly linked with the presence of Type D personality (β = -0.290; p = 0.006; β = -0.282; p = 0.008 respectively), even after controlling for confounders (i.e., sex, age, education, New York Heart Association functional class, beta-blockers and baseline levels of cortisol measures). We found that mental distress, but not fatigue and HRQoL, was linked with blunted cortisol response during anticipation time of psychosocial stress, independently of potential covariates.

Pagina Web:

https://doi.org/10.1038/s41598-022-23712-w

Id prodotto:

130484

Handle IRIS:

11562/1078917

ultima modifica:

23 febbraio 2023

Citazione bibliografica:

Gecaite-Stonciene, Julija; Hughes, Brian M; Kazukauskiene, Nijole; Bunevicius, Adomas; Burkauskas, Julius; Neverauskas, Julius; Bellani, Marcella; Mickuviene, Narseta, Cortisol response to psychosocial stress, mental distress, fatigue and quality of life in coronary artery disease patients «SCIENTIFIC REPORTS» , vol. 12 , n. 19373 , 2022 , pp. 1-12

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo