Pubblicazioni

The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study  (2023)

Autori:
Spinazzola, Edoardo; Quattrone, Diego; Rodriguez, Victoria; Trotta, Giulia; Alameda, Luis; Tripoli, Giada; Gayer-Anderson, Charlotte; Freeman, Tom P; Johnson, Emma C; Jongsma, Hannah E; Stilo, Simona; La Cascia, Caterina; Ferraro, Laura; La Barbera, Daniele; Lasalvia, Antonio; Tosato, Sarah; Tarricone, Ilaria; D'Andrea, Giuseppe; Galatolo, Michela; Tortelli, Andrea; Tagliabue, Ilaria; Turco, Marco; Pompili, Maurizio; Selten, Jean-Paul; de Haan, Lieuwe; Rossi Menezes, Paulo; Del Ben, Cristina M; Santos, Jose Luis; Arrojo, Manuel; Bobes, Julio; Sanjuán, Julio; Bernardo, Miguel; Arango, Celso; Kirkbride, James B; Jones, Peter B; O'Donovan, Michael; Rutten, Bart P; Van Os, Jim; Morgan, Craig; Sham, Pak C; Austin-Zimmerman, Isabelle; Li, Zhikun; Vassos, Evangelos; Murray, Robin M; Di Forti, Marta
Titolo:
The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study
Anno:
2023
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
A Stampa
Referee:
Nome rivista:
Psychological Medicine
ISSN Rivista:
0033-2917
N° Volume:
53
Numero o Fascicolo:
15
Intervallo pagine:
7418-7427
Parole chiave:
Cannabis use; path analysis; psychotic disorders
Breve descrizione dei contenuti:
Background: While cannabis use is a well-established risk factor for psychosis, little is known about any association between reasons for first using cannabis (RFUC) and later patterns of use and risk of psychosis. Methods: We used data from 11 sites of the multicentre European Gene-Environment Interaction (EU-GEI) case-control study. 558 first-episode psychosis patients (FEPp) and 567 population controls who had used cannabis and reported their RFUC.We ran logistic regressions to examine whether RFUC were associated with first-episode psychosis (FEP) case-control status. Path analysis then examined the relationship between RFUC, subsequent patterns of cannabis use, and case-control status. Results: Controls (86.1%) and FEPp (75.63%) were most likely to report 'because of friends' as their most common RFUC. However, 20.1% of FEPp compared to 5.8% of controls reported: 'to feel better' as their RFUC (χ2 = 50.97; p < 0.001). RFUC 'to feel better' was associated with being a FEPp (OR 1.74; 95% CI 1.03-2.95) while RFUC 'with friends' was associated with being a control (OR 0.56; 95% CI 0.37-0.83). The path model indicated an association between RFUC 'to feel better' with heavy cannabis use and with FEPp-control status. Conclusions: Both FEPp and controls usually started using cannabis with their friends, but more patients than controls had begun to use 'to feel better'. People who reported their reason for first using cannabis to 'feel better' were more likely to progress to heavy use and develop a psychotic disorder than those reporting 'because of friends'.
Pagina Web:
https://doi.org/10.1017/s0033291723001071
Id prodotto:
134376
Handle IRIS:
11562/1096573
ultima modifica:
13 gennaio 2024
Citazione bibliografica:
Spinazzola, Edoardo; Quattrone, Diego; Rodriguez, Victoria; Trotta, Giulia; Alameda, Luis; Tripoli, Giada; Gayer-Anderson, Charlotte; Freeman, Tom P; Johnson, Emma C; Jongsma, Hannah E; Stilo, Simona; La Cascia, Caterina; Ferraro, Laura; La Barbera, Daniele; Lasalvia, Antonio; Tosato, Sarah; Tarricone, Ilaria; D'Andrea, Giuseppe; Galatolo, Michela; Tortelli, Andrea; Tagliabue, Ilaria; Turco, Marco; Pompili, Maurizio; Selten, Jean-Paul; de Haan, Lieuwe; Rossi Menezes, Paulo; Del Ben, Cristina M; Santos, Jose Luis; Arrojo, Manuel; Bobes, Julio; Sanjuán, Julio; Bernardo, Miguel; Arango, Celso; Kirkbride, James B; Jones, Peter B; O'Donovan, Michael; Rutten, Bart P; Van Os, Jim; Morgan, Craig; Sham, Pak C; Austin-Zimmerman, Isabelle; Li, Zhikun; Vassos, Evangelos; Murray, Robin M; Di Forti, Marta, The association between reasons for first using cannabis, later pattern of use, and risk of first-episode psychosis: the EU-GEI case-control study «Psychological Medicine» , vol. 53 , n. 152023pp. 7418-7427

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