Publications

Authors:

Sideli, Lucia; Aas, Monica; Quattrone, Diego; La Barbera, Daniele; La Cascia, Caterina; Ferraro, Laura; Alameda, Luis; Velthorst, Eva; Trotta, Giulia; Tripoli, Giada; Schimmenti, Adriano; Fontana, Andrea; Gayer-Anderson, Charlotte; Stilo, Simona; Seminerio, Fabio; Sartorio, Crocettarachele; Marrazzo, Giovanna; Lasalvia, Antonio; Tosato, Sarah; Tarricone, Ilaria; Berardi, Domenico; D'Andrea, Giuseppe; Arango, Celso; Arrojo, Manuel; Bernardo, Miguel; Bobes, Julio; Sanjuán, Julio; Santos, Jose Luis; Menezes, Paulo Rossi; Del-Ben, Cristina Marta; Jongsma, Hannah E; Jones, Peter B; Kirkbride, James B; Llorca, Pierre-Michel; Tortelli, Andrea; Pignon, Baptiste; de Haan, Lieuwe; Selten, Jean-Paul; Van Os, Jim; Rutten, Bart P; Bentall, Richard; Di Forti, Marta; Murray, Robin M; Morgan, Craig; Fisher, Helen L

Title:

The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study

Year:

2023

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

Social Psychiatry and Psychiatric Epidemiology

ISSN of journal:

0933-7954

N° Volume:

First published online: 19 June 2023

Page numbers:

1-8

Keyword:

Childhood adversity; Cognition; Family history of psychosis; First episode; Polygenic risk score; Psychosis

Short description of contents:

This study investigated if the association between childhood maltreatment and cognition among psychosis patients and community controls was partially accounted for by genetic liability for psychosis. Patients with first-episode psychosis (N = 755) and unaffected controls (N = 1219) from the EU-GEI study were assessed for childhood maltreatment, intelligence quotient (IQ), family history of psychosis (FH), and polygenic risk score for schizophrenia (SZ-PRS). Controlling for FH and SZ-PRS did not attenuate the association between childhood maltreatment and IQ in cases or controls. Findings suggest that these expressions of genetic liability cannot account for the lower levels of cognition found among adults maltreated in childhood.

Web page:

https://doi.org/10.1007/s00127-023-02513-0

Product ID:

134428

Handle IRIS:

11562/1097247

Last Modified:

August 25, 2023

Bibliographic citation:

Sideli, Lucia; Aas, Monica; Quattrone, Diego; La Barbera, Daniele; La Cascia, Caterina; Ferraro, Laura; Alameda, Luis; Velthorst, Eva; Trotta, Giulia; Tripoli, Giada; Schimmenti, Adriano; Fontana, Andrea; Gayer-Anderson, Charlotte; Stilo, Simona; Seminerio, Fabio; Sartorio, Crocettarachele; Marrazzo, Giovanna; Lasalvia, Antonio; Tosato, Sarah; Tarricone, Ilaria; Berardi, Domenico; D'Andrea, Giuseppe; Arango, Celso; Arrojo, Manuel; Bernardo, Miguel; Bobes, Julio; Sanjuán, Julio; Santos, Jose Luis; Menezes, Paulo Rossi; Del-Ben, Cristina Marta; Jongsma, Hannah E; Jones, Peter B; Kirkbride, James B; Llorca, Pierre-Michel; Tortelli, Andrea; Pignon, Baptiste; de Haan, Lieuwe; Selten, Jean-Paul; Van Os, Jim; Rutten, Bart P; Bentall, Richard; Di Forti, Marta; Murray, Robin M; Morgan, Craig; Fisher, Helen L, The relationship between genetic liability, childhood maltreatment, and IQ: findings from the EU-GEI multicentric case-control study «Social Psychiatry and Psychiatric Epidemiology» , vol. First published online: 19 June 2023 , 2023 , pp. 1-8

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