Pubblicazioni

Autori:

Defazio, G; Gigante, Af; Erro, R; Belvisi, D; Esposito, M; Trinchillo, A; De Joanna, G; Ceravolo, R; Mazzucchi, S; Unti, E; Barone, P; Scannapieco, S; Cotelli, Ms; Turla, M; Bianchi, M; Bertolasi, L; Pisani, A; Valentino, F; Altavista, Mc; Moschella, V; Girlanda, P; Terranova, C; Bono, F; Spano, G; Fabbrini, G; Ferrazzano, G; Albanese, A; Castagna, A; Cassano, D; Moja, Mc; Pellicciari, R; Bentivoglio, Ar; Eleopra, R; Cossu, G; Ercoli, T; Mascia, Mm; Di Biasio, F; Misceo, S; Magistrelli, L; Romano, M; Scaglione, Clm; Tinazzi, M; Maderna, L; Zibetti, M; Berardelli, A

Titolo:

Phenotypic variability in acquired and idiopathic dystonia

Anno:

2023

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

MOVEMENT DISORDERS CLINICAL PRACTICE

ISSN Rivista:

2330-1619

N° Volume:

10

Numero o Fascicolo:

7

Intervallo pagine:

1107-1113

Parole chiave:

clinical phenomenology; acquired; idiopathic; dystonia

Breve descrizione dei contenuti:

BackgroundTo date, a few studies have systematically investigated differences in the clinical spectrum between acquired and idiopathic dystonias. ObjectivesTo compare demographic data and clinical features in patients with adult-onset acquired and idiopathic dystonias. MethodsPatients were identified from among those included in the Italian Dystonia Registry, a multicenter Italian dataset of patients with adult-onset dystonia. Study population included 116 patients with adult-onset acquired dystonia and 651 patients with isolated adult-onset idiopathic dystonia. ResultsComparison of acquired and idiopathic dystonia revealed differences in the body distribution of dystonia, with oromandibular dystonia, limb and trunk dystonia being more frequent in patients with acquired dystonia. The acquired dystonia group was also characterized by lower age at dystonia onset, greater tendency to spread, lower frequency of head tremor, sensory trick and eye symptoms, and similar frequency of neck pain associated with CD and family history of dystonia/tremor. ConclusionsThe clinical phenomenology of dystonia may differ between acquired and idiopathic dystonia, particularly with regard to the body localization of dystonia and the tendency to spread. This dissimilarity raises the possibility of pathophysiological differences between etiologic categories.

Pagina Web:

https://doi.org/10.1002/mdc3.13801

Id prodotto:

134734

Handle IRIS:

11562/1099851

ultima modifica:

26 luglio 2023

Citazione bibliografica:

Defazio, G; Gigante, Af; Erro, R; Belvisi, D; Esposito, M; Trinchillo, A; De Joanna, G; Ceravolo, R; Mazzucchi, S; Unti, E; Barone, P; Scannapieco, S; Cotelli, Ms; Turla, M; Bianchi, M; Bertolasi, L; Pisani, A; Valentino, F; Altavista, Mc; Moschella, V; Girlanda, P; Terranova, C; Bono, F; Spano, G; Fabbrini, G; Ferrazzano, G; Albanese, A; Castagna, A; Cassano, D; Moja, Mc; Pellicciari, R; Bentivoglio, Ar; Eleopra, R; Cossu, G; Ercoli, T; Mascia, Mm; Di Biasio, F; Misceo, S; Magistrelli, L; Romano, M; Scaglione, Clm; Tinazzi, M; Maderna, L; Zibetti, M; Berardelli, A, Phenotypic variability in acquired and idiopathic dystonia «MOVEMENT DISORDERS CLINICAL PRACTICE» , vol. 10 , n. 7 , 2023 , pp. 1107-1113

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo