Publications

Authors:

Ius, Tamara; Raffa, Giovanni; Aiudi, Denis; Panciani, Pier Paolo; Della Pepa, Giuseppe Maria; Pessina, Federico; Solari, Domenico; Somma, Teresa; Angileri, Filippo Flavio; Nichelatti, Michele; Cappabianca, Paolo; Esposito, Vincenzo; Fornari, Maurizio; Iacopino, Domenico Gerardo; Olivi, Alessandro; Sala, Francesco; Cavallo, Luigi Maria; La Camera, Alessandro

Title:

From data to practice: brain meningioma treatment in elderly patients - a survey of the Italian Society of Neurosurgery (SINch®) and systematic review and meta-analysis

Year:

2024

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

NEUROSURGICAL REVIEW

ISSN of journal:

0344-5607

N° Volume:

47

Number or Folder:

373

Page numbers:

1-17

Keyword:

Aging; Elderly; Meningioma; Morbidity; Mortality; Outcome; Radiosurgery; Surgery

Short description of contents:

The management of meningioma in elderly patients (MEP) presents a complex and evolving challenge. Data available offer conflicting information on treatment options and complications. This survey aimed to examine the current approach to MEP, comparing the national profile to data in the current literature. A survey addressing the treatments options and management of meningioma in elderly was designed on behalf of SINch® (Società Italiana di Neurochirurgia) and sent via email to all Chiefs of Neurosurgical Departments. The survey remained open for responses from May 5th, 2022, until November 21st, 2022. A search of the literature published between January 2000 and March 2023, in accordance to PRISMA guidelines, was included. A total of 51 Neurosurgical centers participated in the survey. The caseload profile of each center influences the choice of treatment selection (Stereotactic Radiosurgery versus open surgery) (p = 0.01) and the consolidated practice of discussing cases within a multidisciplinary group (p = 0.02). The pooled meta-analysis demonstrated a significant increased risk in the elderly group for permanent deficits (p < 0.00001), postoperative infections (p = 0.0004) and hemorrhage (p = 0.0001), perioperative mortality (p < 0.00001), and medical complications (p < 0.00001) as compared to the young population. This study presents the initial comprehensive analysis of the existing trends in the surgical management of MEP in Italy. The significant variation in practices primarily stems from the absence of standardized guidelines. While most centers have adopted an integrated approach, there is a need to promote a multidisciplinary care model. Prospective studies are needed to gather robust evidence in this clinical setting.

Web page:

https://doi.org/10.1007/s10143-024-02524-8

Product ID:

140729

Handle IRIS:

11562/1132946

Last Modified:

October 10, 2024

Bibliographic citation:

Ius, Tamara; Raffa, Giovanni; Aiudi, Denis; Panciani, Pier Paolo; Della Pepa, Giuseppe Maria; Pessina, Federico; Solari, Domenico; Somma, Teresa; Angileri, Filippo Flavio; Nichelatti, Michele; Cappabianca, Paolo; Esposito, Vincenzo; Fornari, Maurizio; Iacopino, Domenico Gerardo; Olivi, Alessandro; Sala, Francesco; Cavallo, Luigi Maria; La Camera, Alessandro, From data to practice: brain meningioma treatment in elderly patients - a survey of the Italian Society of Neurosurgery (SINch®) and systematic review and meta-analysis «NEUROSURGICAL REVIEW» , vol. 47 , n. 373 , 2024 , pp. 1-17

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