Publications

Authors:

Keir, Daniel A; Pogliaghi, Silvia; Inglis, Erin Calaine; Murias, Juan M; Iannetta, Danilo

Title:

The respiratory compensation point: mechanisms and relation to the maximal metabolic steady state

Year:

2024

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

SPORTS MEDICINE

ISSN of journal:

0112-1642

N° Volume:

54

Number or Folder:

12

Page numbers:

2993-3003

Keyword:

n/a

Short description of contents:

At a point during the latter third of an incremental exercise protocol, ventilation begins to exceed the rate of clearance of carbon dioxide (CO2) at the lungs (V-center dot\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\dot{V}}$$\end{document}CO2). The onset of this hyperventilation, which is confirmed by a fall from a period of stability in end-tidal and arterial CO2 tensions (PCO2), is referred to as the respiratory compensation point (RCP). The mechanisms that contribute to the RCP remain debated as does its surrogacy for the maximal metabolic steady state of constant-power exercise (i.e., the highest work rate associated with maintenance of physiological steady state). The objective of this current opinion is to summarize the original research contributions that support and refute the hypotheses that: (i) the RCP represents a rapid, peripheral chemoreceptor-mediated reflex response engaged when the metabolic rate at which the buffering systems can no longer constrain the rise in hydrogen ions ([H+]) associated with rising lactate concentration and metabolic CO2 production is surpassed; and (ii) the metabolic rate at which this occurs is equivalent to the maximal metabolic steady state of constant power exercise. In doing so, we will shed light on potential mechanisms contributing to the RCP, attempt to reconcile disparate findings, make a case for its adoption for exercise intensity stratification and propose strategies for the use of RCP in aerobic exercise prescription.

Web page:

https://doi.org/10.1007/s40279-024-02084-3

Product ID:

141575

Handle IRIS:

11562/1141206

Last Modified:

December 4, 2024

Bibliographic citation:

Keir, Daniel A; Pogliaghi, Silvia; Inglis, Erin Calaine; Murias, Juan M; Iannetta, Danilo, The respiratory compensation point: mechanisms and relation to the maximal metabolic steady state «SPORTS MEDICINE» , vol. 54 , n. 12 , 2024 , pp. 2993-3003

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