Advances in diagnosis, classification, and management of pain in Parkinson's disease
(2025)
Authors:
Tinazzi, Michele; Gandolfi, Marialuisa; Artusi, Carlo Alberto; Bannister, Kirsty; Rukavina, Katarina; Brefel-Courbon, Christine; de Andrade, Daniel Ciampi; Perez-Lloret, Santiago; Mylius, Veit
Title:
Advances in diagnosis, classification, and management of pain in Parkinson's disease
Year:
2025
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Format:
A Stampa
Referee:
Sì
Name of journal:
LANCET NEUROLOGY
ISSN of journal:
1474-4422
N° Volume:
24
Number or Folder:
4
Page numbers:
331-347
Keyword:
Parkinson’s disease; pain; classification of pain; treatment approaches
Short description of contents:
With over 10 million people affected worldwide, Parkinson's disease is the fastest-growing neurological disorder. More than two-thirds of people with Parkinson's disease live with chronic pain, which can manifest in various stages of the disease, substantially affecting daily activities and quality of life. The Parkinson's disease Pain Classification System overcomes the limitations of previous classification systems by distinguishing between pain related to Parkinson's disease and unrelated pain, while also incorporating clinical and pathophysiological (mechanistic) descriptors such as nociceptive, neuropathic, and nociplastic pain. This system provides a framework for accurate diagnosis and mechanism-based therapy. Alongside the appropriate classification of pain, consideration of treatment approaches that include non-invasive (pharmacological and non-pharmacological) and invasive strategies tailored to specific types of pain will refine and inform research trials and clinical practice when it comes to treating pain in Parkinson's disease.
Note:
Michele Tinazzi and Marialuisa Gandolfi contributed equally
Tinazzi, Michele; Gandolfi, Marialuisa; Artusi, Carlo Alberto; Bannister, Kirsty; Rukavina, Katarina; Brefel-Courbon, Christine; de Andrade, Daniel Ciampi; Perez-Lloret, Santiago; Mylius, Veit,
Advances in diagnosis, classification, and management of pain in Parkinson's disease«LANCET NEUROLOGY»
, vol. 24
, n. 4
, 2025
, pp. 331-347