Publications

Authors:

Zipeto, Donato; Matucci, Andrea; Rossolillo, Paola; Ripamonti, C; Scarlatti, C; Lopalco, L; Hazan, U; Bertazzoni, U.

Title:

Fusion complexes and CD4-independent gp120s for the induction of HIV-1 neutralizing antibodies

Year:

2005

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

Retrovirology

ISSN of journal:

1742-4690

N° Volume:

2

Page numbers:

S121-S121

Keyword:

fusion complexes gp120 HIV neutralizing antibodies

Short description of contents:

The narrow spectrum of HIV-specific neutralizing anti- bodies points to the need for new immunogens based on highly conserved epitopes. HIV-1 infects host cells by membrane fusion: during this process conserved epitopes are exposed on the viral glycoprotein gp120/41 that may be used as targets for the induction of antibodies against HIV-1. Neutralizing antibodies against different heterolo- gous HIV-1 isolates may be obtained by immunizing mice with fusion complexes on which conserved epitopes have been stabilized by fixation, or with gp120/41s with a CD4-independent phenotype on which these conserved epitopes may be already exposed.

Web page:

http://www.retrovirology.com/content/2/S1/S121

Product ID:

40293

Handle IRIS:

11562/236864

Deposited On:

June 21, 2012

Last Modified:

November 9, 2022

Bibliographic citation:

Zipeto, Donato; Matucci, Andrea; Rossolillo, Paola; Ripamonti, C; Scarlatti, C; Lopalco, L; Hazan, U; Bertazzoni, U., Fusion complexes and CD4-independent gp120s for the induction of HIV-1 neutralizing antibodies «Retrovirology» , vol. 2 , 2005 , pp. S121-S121

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo