Pubblicazioni

Autori:

Casati, Stefano; Zoppini, Giacomo; Muggeo, Michele; Marchini, Giorgio

Titolo:

Sustained regression of florid diabetic retinopathy in a patient with Donohue syndrome (leprechaunism).

Anno:

2010

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

European Journal of Ophthalmology

ISSN Rivista:

1120-6721

N° Volume:

20

Numero o Fascicolo:

1

Intervallo pagine:

224-227

Parole chiave:

leprechaunism; retinal neovascularization; argon laser panretinal photocoagulation; follow-up

Breve descrizione dei contenuti:

PURPOSE: Leprechaunism is a rare congenital syndrome caused by mutations of the insulin receptor gene, transmitted in an autosomal recessive pattern. Insulin growth factor-1 (IGF-1) treatment can be a therapeutic option in this syndrome by its insulin-like effects. Nevertheless, it is of note that IGF-1 has also an angiogenic activity.METHODS: Fundus examination by ophthalmoscopy, fluorangiography, and laser treatment were performed.RESULTS: A 17-year-old girl with leprechaunism, under treatment with high doses of insulin, presented a florid diabetic retinopathy. The large neovascularization of the disk regressed after treatment with argon laser panretinal photocoagulation. Five years after treatment, the patient maintained good vision.CONCLUSIONS: This clinical case is of interest for 2 reasons: 1) the large retinal neovascularization was likely due to the high insulin dosages; 2) this is the first case in which a sustained regression of retinal neovascularization has been observed after laser treatment in leprechaunism.

Id prodotto:

53515

Handle IRIS:

11562/337956

depositato il:

11 gennaio 2010

ultima modifica:

27 novembre 2022

Citazione bibliografica:

Casati, Stefano; Zoppini, Giacomo; Muggeo, Michele; Marchini, Giorgio, Sustained regression of florid diabetic retinopathy in a patient with Donohue syndrome (leprechaunism). «European Journal of Ophthalmology» , vol. 20 , n. 1 , 2010 , pp. 224-227

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo