- Authors:
-
Matucci, Andrea; Rossolillo, Paola; Turci, Marco; Racchiolli, Pierpaolo; Siccardi, A. G.; Beretta, A.; Zipeto, Donato
- Title:
-
Presence and role of HLA-C in HIV-1 infection
- Year:
-
2009
- Type of item:
-
Articolo in Rivista
- Tipologia ANVUR:
- Articolo su rivista
- Language:
-
Inglese
- Format:
-
Elettronico
- Referee:
-
No
- Name of journal:
- JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
- ISSN of journal:
- 1525-4135
- N° Volume:
-
51
- :
- Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
- Page numbers:
-
137-137
- Keyword:
-
HIV-1; HLA-C; AIDS
- Short description of contents:
- A whole genome association study reported a SNP at -35Kb from the HLA-C gene strongly associated to HIV-1 viral set point and HLAC expression level (Fellay J. et al., 2007). HLA-C is not down-modulated by HIV-1 Nef and can be specifically incorporated in viral membrane enhancing infectivity and resistance to neutralizing antibodies (Cosma A. et al., 1999). We investigated the role of HLA-C in modulating HIV-1 infectivity using cell fusion and pseudovirus infection models and the interaction between HLA-C and Env at membrane level and in purified fusion complexes.
- Web page:
-
http://journals.lww.com/jaids/Fulltext/2009/06012/137_Presence_and_role_of_HLA_C_in_HIV_1_infection.41.aspx
- Product ID:
-
54911
- Handle IRIS:
-
11562/340250
- Deposited On:
-
June 21, 2012
- Last Modified:
-
November 9, 2022
- Bibliographic citation:
-
Matucci, Andrea; Rossolillo, Paola; Turci, Marco; Racchiolli, Pierpaolo; Siccardi, A. G.; Beretta, A.; Zipeto, Donato,
Presence and role of HLA-C in HIV-1 infection
«JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES»
, vol.
51
,
2009
,
pp. 137-137
Consulta la scheda completa presente nel
repository istituzionale della Ricerca di Ateneo