Publications

Authors:

Matucci, Andrea; Rossolillo, Paola; Turci, Marco; Racchiolli, Pierpaolo; Siccardi, A. G.; Beretta, A.; Zipeto, Donato

Title:

Presence and role of HLA-C in HIV-1 infection

Year:

2009

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

No

Name of journal:

JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

ISSN of journal:

1525-4135

N° Volume:

51

:

Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320

Page numbers:

137-137

Keyword:

HIV-1; HLA-C; AIDS

Short description of contents:

A whole genome association study reported a SNP at -35Kb from the HLA-C gene strongly associated to HIV-1 viral set point and HLAC expression level (Fellay J. et al., 2007). HLA-C is not down-modulated by HIV-1 Nef and can be specifically incorporated in viral membrane enhancing infectivity and resistance to neutralizing antibodies (Cosma A. et al., 1999). We investigated the role of HLA-C in modulating HIV-1 infectivity using cell fusion and pseudovirus infection models and the interaction between HLA-C and Env at membrane level and in purified fusion complexes.

Web page:

http://journals.lww.com/jaids/Fulltext/2009/06012/137_Presence_and_role_of_HLA_C_in_HIV_1_infection.41.aspx

Product ID:

54911

Handle IRIS:

11562/340250

Deposited On:

June 21, 2012

Last Modified:

November 9, 2022

Bibliographic citation:

Matucci, Andrea; Rossolillo, Paola; Turci, Marco; Racchiolli, Pierpaolo; Siccardi, A. G.; Beretta, A.; Zipeto, Donato, Presence and role of HLA-C in HIV-1 infection «JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES» , vol. 51 , 2009 , pp. 137-137

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