Fusion complexes and CD4-independent Env for the induction of broad spectrum neutralizing antibodies against HIV-1
Year:
2011
Type of item:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Language:
Inglese
Format:
Elettronico
Referee:
No
Name of journal:
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
ISSN of journal:
1525-4135
N° Volume:
56
:
Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
Page numbers:
65-65
Keyword:
HIV-1neutralizing antibodyAIDS
Short description of contents:
Broad spectrum neutralizing antibodies against HIV-1 are essential for the development of a humoral anti-AIDS vaccine. We used fusion complexes and CD4-independent gp120 as new immunogens to induce neutralizing antibodies blocking the infectivity of different primary isolates of HIV-1.