Publications

Authors:

Spinelli, C.; Gusson, Elena; Casati, Stefano; Panozzo, G.

Title:

Correlation between foveal choroidal thickness with age, refraction and axial lenght.

Year:

2010

Type of item:

Contributo in atti di convegno

Tipologia ANVUR:

Contributo in Atti di convegno

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

Investigative Ophthalmology and Visual Science

ISSN of journal:

0146-0404

Number or Folder:

51

Congresso:

ARVO 2010 Annual Meeting

Place:

Fort Lauderdale, USA

Period:

May 2-6, 2010

Page numbers:

E-Abstract 1723-null

Keyword:

choroid; myopia; aging

Short description of contents:

Purpose:to correlate foveal choroidal thickness (CT) with age, refraction and axial lenght. Methods:we examined with SD-OCT (OPKO-OTI) 84 healthy subjects ageing between 15 and 83 years with refraction between +2 and -35 Sferical Equivalent. We obtained an horizontal scan at foveal level and measured CT from RPE line to the iperreflective line behind the large vessel layer of the choroid. Axial length (IOL Master, Carl Zeiss Meditec) was also evaluated. We divided the eyes into 3 groups according to the age (GrA <40 yrs; GrB 41-64 yrs; GrC >65 yrs) and in each group CT was correlated with refraction and axial length. Results:After excluding eyes with concomitant pathologies other than high myopia, 143 eyes were evaluated. Ageing was associated with a progressive decrease in CT, from a mean of 305 µm in GrA to 190 µm in GrB and 145 µm in GrC. Increasing myopic refraction and axial length were associated with a progressive CT decrease in each group of age. CT showed a statistical difference between emmetropic eyes (±2 D, mean CT 312 µm) and those presenting simple myopia (<6 D, mean CT 243 µm). Over 16 D, mean CT was 72.5 µm (about four times thinner than in emmetropic eyes). At high levels of myopia however, axial length was more correlated with CT decrease than refractive error. Conclusions:Choroidal thickness progressively decreases according to the age, with a significant loss detectable since the age of forty. High myopia is characterized by a typical and marked choroidal thinning, more correlated to axial length than to refractive error.

Product ID:

66285

Handle IRIS:

11562/391669

Deposited On:

February 29, 2012

Last Modified:

November 1, 2022

Bibliographic citation:

Spinelli, C.; Gusson, Elena; Casati, Stefano; Panozzo, G., Correlation between foveal choroidal thickness with age, refraction and axial lenght. in «Investigative Ophthalmology and Visual Science» n. 51 , Proceedings of "ARVO 2010 Annual Meeting" , Fort Lauderdale, USA , May 2-6, 2010 , 2010 , pp. E-Abstract 1723-null

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