Publications

Authors:

Monaco, Salvatore; Ferrari, Sergio; Gajofatto, Alberto; Zanusso, Gianluigi; Mariotto, Sara

Title:

HCV-related nervous system disorders.

Year:

2012

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

CLINICAL & DEVELOPMENTAL IMMUNOLOGY

ISSN of journal:

1740-2522

N° Volume:

2012

Page numbers:

Article ID 236148-9 pages

Keyword:

chronic infection; chronic hepatitis C; neurological complications; viral infections of central nervous system

Short description of contents:

Chronic infection with hepatitis C virus (HCV) is associated with a wide spectrum of extrahepatic manifestations, affecting different organ systems. Neurological complications occur in a large number of patients and range from peripheral neuropathy to cognitive impairment. Pathogenetic mechanisms responsible for nervous system dysfunction are mainly related to the upregulation of the host immune response with production of autoantibodies, immune complexes, and cryoglobulins. Alternative mechanisms include possible extrahepatic replication of HCV in neural tissues and the effects of circulating inflammatory cytokines and chemokines.

Web page:

http://dx.doi.org/10.1155/2012/236148

Product ID:

72146

Handle IRIS:

11562/448138

Deposited On:

August 23, 2012

Last Modified:

November 17, 2022

Bibliographic citation:

Monaco, Salvatore; Ferrari, Sergio; Gajofatto, Alberto; Zanusso, Gianluigi; Mariotto, Sara, HCV-related nervous system disorders. «CLINICAL & DEVELOPMENTAL IMMUNOLOGY» , vol. 2012 , 2012 , pp. Article ID 236148-9 pages

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