Publications

Authors:

Pieropan, Sara; Biasi, Domenico; Barausse, Giovanni; Facci, M. V.; Tonetta, S.; Ravagnani, Viviana; Carletto, Antonio; Boscaini, Flavio; Boner, Attilio; Sidoti, Grazia; Adami, Silvano; Zoccante, L.

Title:

PAEDIATRIC AUTOIMMUNE NEUROPSYCHIATRIC DISORDER ASSOCIATED WITH GROUP A STREPTOCOCCAL INFECTION (PANDAS): CARDIAC AND ARTICULAR INVOLVEMENT

Year:

2012

Type of item:

Abstract in Atti di convegno

Tipologia ANVUR:

Abstract in Atti di convegno

Language:

Inglese

Format:

Elettronico

Referee:

Sì

Name of journal:

Annals of the Rheumatic Diseases

ISSN of journal:

0003-4967

Congresso:

Annual European Congress of Rheumatology - EULAR 2012

Place:

Berlino

Period:

6-9 giugno 2012

Page numbers:

706-706

Keyword:

group A β-hemolytic streptococcal; PANDAS; Pediatric

Short description of contents:

Background: PANDAS is a syndrome characterized by obsessive-compulsive disorder (OCD) and/or tic disorder with symptom exacerbations in children after group A β-hemolytic streptococcal (GAS) infections. No cardiac nor articular involvement is present as in the case of Sydenham Chorea. Antinuclear antibodies and nuclear basal involvement at brain MR may be encountered. Objectives: We evaluated the possible misdiagnosed cardiac and articular involvement in 30 children affected by PANDAS and regularly assessed at an out-patient ambulatory in the period from 2007 to 2011. Methods: 30 children affected by PANDAS according the Swedo SA diagnostic criteria were evaluated at the out-patient ambulatory of the Rhematologic and Neuropsichiatric departments of Verona's University Hospital in the period from 2007 to 2011; thorough cardiologic evaluation encompassing ECG and echocardiogram was performed Results: mean age of the 30 young patients (M:F 23:7) was 7±3 years; all had sierologic evidence of previous streptococcal infection; ECG was normal in all the cases as well as cardiac echogram with the exception of 2 cases of trivial mitral regurgitation without structural valvular alterations; no patient was affected by perferic arthritis, arthargias nor morning stiffness. Conclusions: the absence of cardiac or articular involvement in PANDAS patients, as evidenced in this study, confirms its differential diagnosis with Sydenham Chorea

Product ID:

75988

Handle IRIS:

11562/505552

Deposited On:

January 28, 2013

Last Modified:

November 14, 2022

Bibliographic citation:

Pieropan, Sara; Biasi, Domenico; Barausse, Giovanni; Facci, M. V.; Tonetta, S.; Ravagnani, Viviana; Carletto, Antonio; Boscaini, Flavio; Boner, Attilio; Sidoti, Grazia; Adami, Silvano; Zoccante, L., PAEDIATRIC AUTOIMMUNE NEUROPSYCHIATRIC DISORDER ASSOCIATED WITH GROUP A STREPTOCOCCAL INFECTION (PANDAS): CARDIAC AND ARTICULAR INVOLVEMENT in «Annals of the Rheumatic Diseases» , Proceedings of "Annual European Congress of Rheumatology - EULAR 2012" , Berlino , 6-9 giugno 2012 , 2012 , pp. 706-706

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