Publications

Authors:

Zoppini, Giacomo; Cacciatori, Vittorio; Raimondo, Daniele; Gemma, Marialuisa; Trombetta, Maddalena; Dauriz, Marco; Brangani, Corinna; Pichiri, Isabella; Negri, Carlo; Stoico, Vincenzo; Bergamini, Corinna; Targher, Giovanni; Santi, Lorenza; Thomaseth, Karl; Bellavere, Federico; Bonadonna, Riccardo C; Bonora, Enzo

Title:

Prevalence of Cardiovascular Autonomic Neuropathy in a Cohort of Patients With Newly Diagnosed Type 2 Diabetes: The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS)

Year:

2015

Type of item:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Language:

Inglese

Format:

A Stampa

Referee:

Sì

Name of journal:

Diabetes Care

ISSN of journal:

0149-5992

N° Volume:

38

Number or Folder:

8

Page numbers:

1487-1493

Keyword:

Type 2 diabetes; cardiac autonomic neuropathy

Short description of contents:

OBJECTIVE: Cardiovascular autonomic diabetic neuropathy (CAN) is a serious complication of diabetes. No reliable data on the prevalence of CAN among patients with newly diagnosed type 2 diabetes are available. Therefore, the aim of this study was to estimate the prevalence of CAN among patients with newly diagnosed type 2 diabetes.RESEARCH DESIGN AND METHODS:A cohort of 557 patients with newly diagnosed type 2 diabetes with cardiovascular autonomic test results available was selected. Early and confirmed neuropathy were assessed using a standardized methodology and their prevalences determined. A multivariate logistic regression analysis was modeled to study the factors associated with CAN.RESULTS:In the entire cohort, the prevalence of confirmed CAN was 1.8%, whereas that of early CAN was 15.3%. Prevalence did not differ between men and women. In the multivariate analyses BMI results were independently and significantly associated with CAN after adjusting for age, sex, hemoglobin A1c, pulse pressure, triglyceride-to-HDL cholesterol ratio, kidney function parameters, and antihypertensive treatment.CONCLUSIONS:CAN could be detected very early in type 2 diabetes. This study may suggest the importance of performing standardized cardiovascular autonomic tests after diagnosis of type 2 diabetes.

Product ID:

87850

Handle IRIS:

11562/925954

Last Modified:

October 30, 2024

Bibliographic citation:

Zoppini, Giacomo; Cacciatori, Vittorio; Raimondo, Daniele; Gemma, Marialuisa; Trombetta, Maddalena; Dauriz, Marco; Brangani, Corinna; Pichiri, Isabella; Negri, Carlo; Stoico, Vincenzo; Bergamini, Corinna; Targher, Giovanni; Santi, Lorenza; Thomaseth, Karl; Bellavere, Federico; Bonadonna, Riccardo C; Bonora, Enzo, Prevalence of Cardiovascular Autonomic Neuropathy in a Cohort of Patients With Newly Diagnosed Type 2 Diabetes: The Verona Newly Diagnosed Type 2 Diabetes Study (VNDS) «Diabetes Care» , vol. 38 , n. 8 , 2015 , pp. 1487-1493

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo