Pubblicazioni

Autori:

Carton, Flavia; Malatesta, Manuela

Titolo:

Nanotechnological research for regenerative medicine: the role of hyaluronic acid

Anno:

2024

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ISSN Rivista:

1422-0067

N° Volume:

25

Numero o Fascicolo:

7

Intervallo pagine:

1-16

Parole chiave:

hyaluronic acid; hyaluronan; tissue engineering; hydrogel; nanoparticle; cartilage regeneration; bone regeneration; wound healing; angiogenesis; neural regeneration

Breve descrizione dei contenuti:

Hyaluronic acid (HA) is a linear, anionic, non-sulfated glycosaminoglycan occurring in almost all body tissues and fluids of vertebrates including humans. It is a main component of the extracellular matrix and, thanks to its high water-holding capacity, plays a major role in tissue hydration and osmotic pressure maintenance, but it is also involved in cell proliferation, differentiation and migration, inflammation, immunomodulation, and angiogenesis. Based on multiple physiological effects on tissue repair and reconstruction processes, HA has found extensive application in regenerative medicine. In recent years, nanotechnological research has been applied to HA in order to improve its regenerative potential, developing nanomedical formulations containing HA as the main component of multifunctional hydrogels systems, or as core component or coating/functionalizing element of nanoconstructs. This review offers an overview of the various uses of HA in regenerative medicine aimed at designing innovative nanostructured devices to be applied in various fields such as orthopedics, dermatology, and neurology.

Pagina Web:

https://doi.org/10.3390/ijms25073975

Id prodotto:

139017

Handle IRIS:

11562/1124731

ultima modifica:

15 giugno 2024

Citazione bibliografica:

Carton, Flavia; Malatesta, Manuela, Nanotechnological research for regenerative medicine: the role of hyaluronic acid «INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES» , vol. 25 , n. 7 , 2024 , pp. 1-16

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