Olfactory mucosa brushing coupled with RT-QuIC: a potential and innovative test for intravital definite diagnosis of Creutzfeldt Jakob disease

Data inizio
1 gennaio 2014
Durata (mesi) 
12
Dipartimenti
Neuroscienze, Biomedicina e Movimento
Responsabili (o referenti locali)
Zanusso Gianluigi

Aim of the present project is to provide a standard procedure for OM sampling and to analyse the sensitivity and the specificity of OM brushing/RT-QuIC test in a large cohort of patients with sporadic CJD and genetic CJD.
Its purpose is to foster and validate a diagnostic test for the definite intravital diagnosis of Creutzfeldt – Jakob disease (CJD) based on the identification of the pathological prion protein (PrPCJD) in the olfactory mucosa (OM) collected by nasal brushing.

Enti finanziatori:

The Foundation pour la Recherche Medicale (FRM)
Finanziamento: assegnato e gestito dal Dipartimento

Partecipanti al progetto

Matilde Bongianni
Michele Fiorini
Ricercatore a tempo determinato
Gianluigi Zanusso
Professore associato

Allegati

Allegati
  • pdf   Progetto   (pdf, it, 59 KB, 26/03/14)

Attività

Strutture