Pubblicazioni

Fusion complexes and CD4-independent gp120s for the induction of HIV-1 neutralizing antibodies  (2005)

Autori:
D. ZIPETO; MATUCCI A; ROSSOLILLO P; RIPAMONTI C; SCARLATTI C; LOPALCO L; HAZAN U; BERTAZZONI U
Titolo:
Fusion complexes and CD4-independent gp120s for the induction of HIV-1 neutralizing antibodies
Anno:
2005
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
Elettronico
Referee:
No
Nome rivista:
Retrovirology
ISSN Rivista:
1742-4690
N° Volume:
2
Intervallo pagine:
S121-S121
Parole chiave:
fusion complexes gp120 HIV neutralizing antibodies
Breve descrizione dei contenuti:
The narrow spectrum of HIV-specific neutralizing anti- bodies points to the need for new immunogens based on highly conserved epitopes. HIV-1 infects host cells by membrane fusion: during this process conserved epitopes are exposed on the viral glycoprotein gp120/41 that may be used as targets for the induction of antibodies against HIV-1. Neutralizing antibodies against different heterolo- gous HIV-1 isolates may be obtained by immunizing mice with fusion complexes on which conserved epitopes have been stabilized by fixation, or with gp120/41s with a CD4-independent phenotype on which these conserved epitopes may be already exposed.
Pagina Web:
http://www.retrovirology.com/content/2/S1/S121
Id prodotto:
40293
Handle IRIS:
11562/236864
depositato il:
21 giugno 2012
ultima modifica:
20 marzo 2018
Citazione bibliografica:
D. ZIPETO; MATUCCI A; ROSSOLILLO P; RIPAMONTI C; SCARLATTI C; LOPALCO L; HAZAN U; BERTAZZONI U, Fusion complexes and CD4-independent gp120s for the induction of HIV-1 neutralizing antibodies «Retrovirology» , vol. 22005pp. S121-S121

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