Pubblicazioni

Flavonoid supplements increase neurotrophin activity to modulate inflammation in retinal genetic diseases  (2020)

Autori:
Kiani, Aysha Karim; Falsini, Benedetto; Ziccardi, Lucia; Gusson, Elena; Mangialavori, Domenica; Allegrini, Francesca; Colao, Emma; Bertelli, Matteo
Titolo:
Flavonoid supplements increase neurotrophin activity to modulate inflammation in retinal genetic diseases
Anno:
2020
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
A Stampa
Referee:
Nome rivista:
ACTA BIOMEDICA
ISSN Rivista:
2531-6745
N° Volume:
91
Numero o Fascicolo:
13-S
Intervallo pagine:
1-5
Parole chiave:
retinal degenerative disorders; neurotrophin synthesis; flavonoids supplementation; anti-inflammation; anti-oxidant
Breve descrizione dei contenuti:
Retinal degenerative disorders induce loss of photoreceptors associated with inflammation, and negative remodeling and plasticity of neural retina. Retinal degenerative diseases may have genetic and/or environmental causes. Degeneration of retinal pigment epithelium cells initiates a vicious circle increasing the ongoing inflammation in both retina and choroid. Flavonoids are polyphenolic molecules with antioxidant activity and dietary intake, specifically of anthocyanins and flavanols, improves oxidative stress and neuro-inflammation. In vitro and ex vivo studies have also revealed biological effects of flavonoids on retinal protection against oxidative stress and inflammation. In this brief review, the protective role of flavonoids against retinal degeneration and inflammation will be discussed along with their therapeutic potential for the treatment of retinal degenerative diseases.
Pagina Web:
https://doi.org/10.23750/abm.v91i13-S.10683
Id prodotto:
117492
Handle IRIS:
11562/1029615
ultima modifica:
15 novembre 2022
Citazione bibliografica:
Kiani, Aysha Karim; Falsini, Benedetto; Ziccardi, Lucia; Gusson, Elena; Mangialavori, Domenica; Allegrini, Francesca; Colao, Emma; Bertelli, Matteo, Flavonoid supplements increase neurotrophin activity to modulate inflammation in retinal genetic diseases «ACTA BIOMEDICA» , vol. 91 , n. 13-S2020pp. 1-5

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

<<indietro

Attività

Strutture

Condividi