Pubblicazioni

Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study  (2022)

Autori:
Panozzo, Giacomo; Mura, Giulia Dalla; Franzolin, Elia; Giannarelli, Diana; Albano, Valeria; Alessio, Gianni; Arrigo, Alessandro; Casati, Stefano; Cassottana, Paola; Contardi, Cecilia; D'Aloisio, Rossella; Fasce, Francesco; Gusson, Elena; Marchini, Giorgio; Mastropasqua, Leonardo; Niccolò, Massimo; Palmisano, Carmela; Pastore, Marco Rocco; Saviano, Sandro; Tognetto, Daniele; Bandello, Francesco
Titolo:
Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study
Anno:
2022
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
A Stampa
Referee:
Nome rivista:
EYE
ISSN Rivista:
0950-222X
N° Volume:
36
Numero o Fascicolo:
8
Intervallo pagine:
1687-1693
Parole chiave:
Lens diseases; Outcomes research; Retinal diseases
Breve descrizione dei contenuti:
Background: The prospective DIabetes and CATaract Study II (DICAT II) was performed to characterise the risks of cataract surgery to the retinae of patients with early diabetic macular oedema (E-DMO). Methods: DICAT II was a prospective, comparative, multicentre, observational study involving six Italian clinics. Patients were aged ≥55 years, had type 1 or 2 diabetes with spectral-domain optical coherence tomography evidence of ESASO classification Early DMO. Group 1 eyes (78 eyes, 78 patients) underwent phacoemulsification-based cataract surgery. Group 2 eyes (65 eyes, 65 patients) had E-DMO and either clear media or had undergone uncomplicated cataract surgery ≥1 year previously. Central subfield thickness (CST) and best-corrected visual acuity (BCVA) were assessed in both groups. Results: The negative impact of surgery on CST was evident after the first postoperative week; CST peaked during the first month, then rapidly decreased. CST worsening ≥10 µm was observed in 63/78 eyes (80.7%) and 29/65 eyes (44.6%) in Groups 1 and 2, respectively (p < 0.0001). CST worsening of ≥50 µm was observed in 51 eyes (65.4%) and 10 eyes (15.4%) in Groups 1 and 2, respectively (p < 0.0001). Mean CST worsening was lower in Group 2 than in Group 1 (38.6 ± 30.4 µm vs 85.5 ± 55.3 µm, p < 0.0001) with a lower BCVA loss (-2.6 ± 3.5 letters vs -8.2 ± 6.2 letters, p < 0.0001). Higher glycaemic levels and HBA1c levels were significantly associated with the risk of >50 μm CST worsening in eyes from both groups. Conclusion: Early DMO is associated with poorer outcomes after cataract surgery and requires close pre- and postoperative monitoring.
Pagina Web:
https://doi.org/10.1038/s41433-021-01718-4
Id prodotto:
122078
Handle IRIS:
11562/1047352
ultima modifica:
8 novembre 2022
Citazione bibliografica:
Panozzo, Giacomo; Mura, Giulia Dalla; Franzolin, Elia; Giannarelli, Diana; Albano, Valeria; Alessio, Gianni; Arrigo, Alessandro; Casati, Stefano; Cassottana, Paola; Contardi, Cecilia; D'Aloisio, Rossella; Fasce, Francesco; Gusson, Elena; Marchini, Giorgio; Mastropasqua, Leonardo; Niccolò, Massimo; Palmisano, Carmela; Pastore, Marco Rocco; Saviano, Sandro; Tognetto, Daniele; Bandello, Francesco, Early DMO: a predictor of poor outcomes following cataract surgery in diabetic patients. The DICAT-II study «EYE» , vol. 36 , n. 82022pp. 1687-1693

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

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