Pubblicazioni

Autori:

Franzolin, Elia; Gusson, Elena; Panozzo, Giacomo

Titolo:

The effect of pars plana vitrectomy with internal limiting membrane peeling on the durability of the intravitreal dexamethasone implant in the treatment of diabetic macular edema

Anno:

2022

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

AMERICAN JOURNAL OF OPHTHALMOLOGY. CASE REPORTS

ISSN Rivista:

2451-9936

N° Volume:

26

Numero o Fascicolo:

101401

Intervallo pagine:

1-4

Parole chiave:

Dexamethasone intravitreal implant; Diabetes; Diabetic macular edema; Internal limiting membrane peeling; Pars plana vitrectomy

Breve descrizione dei contenuti:

Purpose: To evaluate the influence of pars plana vitrectomy with internal limiting membrane peeling on recurrence time of diabetic macular edema in eyes under treatment with dexamethasone intravitreal implant injections. Material and methods: Twelve pseudophakic eyes of 12 patients with non-proliferative diabetic retinopathy and non-tractional diabetic macular edema were included. All eyes had already been treated with two or more dexamethasone intravitreal implant injections evidencing a recurrence time of three months or less (early recurrence). At baseline, they underwent pars plana vitrectomy with internal limiting membrane peeling, ending with dexamethasone intravitreal implant injection. Patients were then followed-up monthly, treated with a second injection at the first recurrence, and followed up to the second recurrence. Measurements of best corrected visual acuity, intraocular pressure, and central foveal thickness by spectral-domain optical coherence tomography were performed at each follow-up examination. Results: Vitrectomized eyes showed a significant extension of recurrence time of diabetic macular edema, and specifically from 3.4 (3.2-3.7) to 6.5 (5.7-8.2) months after the first injection, and to 7.0 (5.7-8.2) months (p < 0.01) after the second injection (p < 0.01). Conclusions and importance: Pars plana vitrectomy with internal limiting membrane peeling seems not to influence functional and anatomical results in eyes under treatment with dexamethasone intravitreal implant injections for diabetic macular edema, but appears to significantly extend the benefit of the drug.

Pagina Web:

https://doi.org/10.1016/j.ajoc.2022.101401

Id prodotto:

125306

Handle IRIS:

11562/1059615

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Franzolin, Elia; Gusson, Elena; Panozzo, Giacomo, The effect of pars plana vitrectomy with internal limiting membrane peeling on the durability of the intravitreal dexamethasone implant in the treatment of diabetic macular edema «AMERICAN JOURNAL OF OPHTHALMOLOGY. CASE REPORTS» , vol. 26 , n. 101401 , 2022 , pp. 1-4

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo