Pubblicazioni

Autori:

Maniscalco, Giorgia Teresa; Ziello, Antonio Rosario; Mantovani, Elisa; Dinoto, Alessandro; Di Giulio Cesare, Daniele; Moreggia, Ornella; Di Battista, Maria Elena; Carta, Sara; Chiodega, Vanessa; Stoppele, Emanuela; Ferrari, Sergio; Andreone, Vincenzo; Tamburin, Stefano; Mariotto, Sara

Titolo:

Cognitive Profile in Adult Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Comparative Study With Multiple Sclerosis

Anno:

2025

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

Elettronico

Referee:

Sì

Nome rivista:

European Journal Of Neurology

ISSN Rivista:

1351-5101

N° Volume:

32

Numero o Fascicolo:

3

Intervallo pagine:

1-5

Parole chiave:

cognition; multiple sclerosis (MS); myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD); neuropsychological battery

Breve descrizione dei contenuti:

Background: Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) has emerged as an acquired immune-mediated demyelinating disorder of the central nervous system distinct from multiple sclerosis (MS). Cognitive dysfunction and related symptoms (anxiety, depression, fatigue) and their impact on quality of life (QoL) have been in-depth characterized in MS, but data in adult MOGAD patients are very preliminary. Methods: This study aims to characterize cognitive changes through an extensive cognitive battery, as well as anxiety, depression, fatigue, and QoL, in adult MOGAD compared to MS patients. Results: Cognitive outcomes (number of patients with abnormal scores, score severity) depression, anxiety, fatigue, and QoL were largely comparable between MOGAD and MS patients. Most cognitive outcomes were not significantly correlated with neuropsychiatric symptoms, fatigue, and QOL in MOGAD. Conclusions: Our study underscores the importance of cognitive and related outcomes in MOGAD patients and the need for future studies exploring their pathophysiological and cortical morphometric underpinnings and potential therapeutic approaches.

Note:

Giorgia Teresa Maniscalco and Antonio Rosario Ziello share first authorship. Stefano Tamburin and Sara Mariotto share senior authorship.

Pagina Web:

https://doi.org/10.1111/ene.70115

Id prodotto:

144925

Handle IRIS:

11562/1158668

ultima modifica:

28 maggio 2025

Citazione bibliografica:

Maniscalco, Giorgia Teresa; Ziello, Antonio Rosario; Mantovani, Elisa; Dinoto, Alessandro; Di Giulio Cesare, Daniele; Moreggia, Ornella; Di Battista, Maria Elena; Carta, Sara; Chiodega, Vanessa; Stoppele, Emanuela; Ferrari, Sergio; Andreone, Vincenzo; Tamburin, Stefano; Mariotto, Sara, Cognitive Profile in Adult Patients With Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease: A Comparative Study With Multiple Sclerosis «European Journal Of Neurology» , vol. 32 , n. 3 , 2025 , pp. 1-5

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo