Pubblicazioni

Autori:

Bellani, Marcella; Dusi, Nicola; P., Yeh; J. C., Soares; P., Brambilla

Titolo:

The effects of antidepressants on human brain as detected by imaging studies. Focus on major depression.

Anno:

2010

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

Progress in Neuro Psychopharmacology

ISSN Rivista:

0278-5846

N° Volume:

35

Intervallo pagine:

1544-1552

Parole chiave:

MRI; MRS; PET

Breve descrizione dei contenuti:

Recent brain imaging studies have shed light on understanding the pathogenesis of mood disorders. Evidence of structural, chemical, and functional brain changes, particularly in prefrontal cortex, cingulate, and amygdala, has been revealed in major depressive disorder (MDD). Furthermore, imaging techniques have been applied to monitor the effects of antidepressants (ADs) both in the brains of healthy volunteers and MDD patients. Although with some discrepancies due to the differences in study designs and patient samples, imaging findings have shown that ADs, particularly those having effects on the serotonergic system, modulate the volumes, functions and biochemistry of brain structures, i.e. dorsolateral prefrontal cortex, anterior cingulate and amygdala, which have been demonstrated abnormal in MDD by earlier imaging studies. This paper reviews imaging studies conducted in MDD patients and healthy controls treated with different ADs.

Pagina Web:

http://dx.doi.org/10.1016/j.pnpbp.2010.11.040

Id prodotto:

61558

Handle IRIS:

11562/348314

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Bellani, Marcella; Dusi, Nicola; P., Yeh; J. C., Soares; P., Brambilla, The effects of antidepressants on human brain as detected by imaging studies. Focus on major depression. «Progress in Neuro Psychopharmacology» , vol. 35 , 2010 , pp. 1544-1552

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo