Pubblicazioni

Autori:

Brigo, Francesco; Balter, Rita; Marradi, P.; Ferlisi, Monica; Zaccaron, A.; Fiaschi, Antonio; Frasson, E.; Bertolasi, Laura

Titolo:

Vincristine-related neuropathy versus acute inflammatory demyelinating polyradiculoneuropathy in children with acute lymphoblastic leukemia.

Anno:

2012

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

European Journal of Paediatric Neurology

ISSN Rivista:

0883-0738

N° Volume:

27

Numero o Fascicolo:

7

Editore:

Saunders

Intervallo pagine:

867-874

Parole chiave:

Acute inflammatory demyelinating polyradiculoneuropathy; acute lymphoblastic leukemia; electroneurography; chemotherapy; intravenous immunoglobulin; neurophysiological studies; vincristine-induced neuropathy

Breve descrizione dei contenuti:

The objective of this study was to evaluate whether electroneurography could help in differentiating between vincristine-induced neuropathy and acute inflammatory demyelinating polyradiculoneuropathy. We performed electroneurography in 7 children from September 2006 to March 2009 admitted to receive chemotherapy including vincristine for acute lymphoblastic leukemia, in whom severe acute limb weakness developed, suggesting vincristine-induced neuropathy. Three of 7 patients had electroneurography, suggesting acute inflammatory demyelinating polyradiculoneuropathy. They received intravenous immunoglobulins without discontinuing chemotherapy, and within 10 days their electroclinical conditions improved. Although electroneurography showed only absent F waves, preventing us from reaching a definitive neurophysiological diagnosis of acute inflammatory demyelinating polyradiculoneuropathy, children's presenting clinical manifestations, their disease course, and rapid and complete recovery after intravenous immunoglobulins argued strongly in its favor. A prompt, correct differential diagnosis of vincristine neuropathy and acute inflammatory demyelinating polyradiculoneuropathy in patients with acute lymphoblastic leukemia receiving vincristine is essential to improve disease outcome and prolong life expectancy.

Pagina Web:

http://dx.doi.org/10.1177/0883073811428379

Id prodotto:

67819

Handle IRIS:

11562/386436

depositato il:

28 giugno 2012

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Brigo, Francesco; Balter, Rita; Marradi, P.; Ferlisi, Monica; Zaccaron, A.; Fiaschi, Antonio; Frasson, E.; Bertolasi, Laura, Vincristine-related neuropathy versus acute inflammatory demyelinating polyradiculoneuropathy in children with acute lymphoblastic leukemia. «European Journal of Paediatric Neurology» , vol. 27 , n. 7 , 2012 , pp. 867-874

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