Pubblicazioni

Autori:

Morgante, Francesca; Matinella, Angela; Andrenelli, Elisa; Ricciardi, Lucia; Allegra, Cosimo; Terranova, Carmen; Girlanda, Paolo; Tinazzi, Michele

Titolo:

Pain processing in functional and idiopathic dystonia: An exploratory study

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

Movement Disorders

ISSN Rivista:

0885-3185

N° Volume:

33

Numero o Fascicolo:

8

Intervallo pagine:

1340-1348

Parole chiave:

cervical dystonia; emotions; functional movement disorders; pain; psychogenic dystonia

Breve descrizione dei contenuti:

BACKGROUND: Pain is often experienced by patients with functional dystonia and idiopathic cervical dystonia and is likely to be determined by different neural mechanisms. OBJECTIVE: In this exploratory study, we tested the sensory-discriminative and cognitive-emotional component of pain in patients with functional and idiopathic dystonia. METHODS: Ten patients with idiopathic cervical dystonia, 12 patients with functional dystonia, and 16 age- and sex-matched healthy controls underwent psychophysical testing of tactile and pain thresholds and pain tolerance. We delivered electrical pulses of increasing intensity to the index finger of each hand and the halluces of each foot. Pain threshold and pain tolerance were respectively defined as the (1) intensity at which sensation changed from unpainful to faintly painful and (2) intensity at which painful sensation was intolerable. RESULTS: No differences were found between the three groups for tactile and pain thresholds assessed in hands and feet. Pain tolerance was significantly increased in all body regions only in functional dystonia. Patients with continuous functional dystonia had higher pain tolerance compared to subjects with paroxysmal functional dystonia and idiopathic cervical dystonia. There was no correlation between pain tolerance and pain scores, depression, anxiety, disease duration, and motor disability in both groups. CONCLUSIONS: Patients with functional dystonia have a dissociation between the sensory-discriminative and cognitive-emotional components of pain, as revealed by normal pain thresholds and increased pain tolerance. Abnormal connectivity between the motor and limbic systems might account for abnormal pain processing in functional dystonia. © 2018 International Parkinson and Movement Disorder Society. © 2018 International Parkinson and Movement Disorder Society.

Pagina Web:

https://doi.org/10.1002/mds.27402

Id prodotto:

102720

Handle IRIS:

11562/979541

ultima modifica:

15 novembre 2022

Citazione bibliografica:

Morgante, Francesca; Matinella, Angela; Andrenelli, Elisa; Ricciardi, Lucia; Allegra, Cosimo; Terranova, Carmen; Girlanda, Paolo; Tinazzi, Michele, Pain processing in functional and idiopathic dystonia: An exploratory study «Movement Disorders» , vol. 33 , n. 8 , 2018 , pp. 1340-1348

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