Pubblicazioni

Autori:

Danese, Alessandra; Cappellari, Manuel; Pancheri, Elia; Mugnai, Giacomo; Micheletti, Nicola; Tomelleri, Giampaolo; Carletti, Monica; Turri, Giulia; Marafioti, Vincenzo; Monaco, Salvatore; Bonetti, Bruno; Bovi, Paolo

Titolo:

The dispersion of myocardial repolarization in ischemic stroke and intracranial hemorrhage

Anno:

2018

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

Journal of Electrocardiology

ISSN Rivista:

0022-0736

N° Volume:

51

Numero o Fascicolo:

4

Intervallo pagine:

691-695

Parole chiave:

Cerebrovascular event; Miocardial repolarization; QT prolongation; T-peak to end

Breve descrizione dei contenuti:

BACKGROUND: Markers of dispersion of myocardial repolarization have been proposed to identify the patients at higher risk of malignant arrhythmic events. The aim of the present study is to assess a possible association of the electrocardiografic (ECG) markers of the dispersion of repolarization with the type of stroke, involvement of insula, neurological severity (National Institutes of Health Stroke Scale, NIHSS score), and disability (modified Rankin Scale, mRS score) in patients with a cerebrovascular event. METHODS: We conducted a retrospective analysis based on data prospectively collected from consecutive patients with a cerebrovascular event who underwent 12‑lead ECG at admission to the Verona Stroke Unit. RESULTS: Of the 63 patients included in the study, 55 had ischemic stroke and 8 intracranial hemorrhage. TpTe (time between the peak and the end of the T wave) and TpTe/QTc (TpTe/corrected time between the start of the Q wave and the end of the T wave) in lead V5 were higher in intracranial hemorrhage than in ischemic stroke (p = 0.03 and p = 0.04, respectively) and QT max (the longest QT calculated in the 12 leads) was higher in patients with involvement of insula (p ≤ 0.01). A correlation was found between QTc max and NIHSS score at admission (p = 0.02), QT max and NIHSS score at discharge (p = 0.05), and QT max and mRS score at discharge (p = 0.02). CONCLUSIONS: TpTe and TpTe/QTc in V5 lead were associated with intracranial hemorrhage and QT max was associated with involvement of insula. The prolongation of QT was correlated with neurological severity and disability.

Pagina Web:

https://doi.org/10.1016/j.jelectrocard.2018.05.007

Id prodotto:

103831

Handle IRIS:

11562/983699

ultima modifica:

23 febbraio 2023

Citazione bibliografica:

Danese, Alessandra; Cappellari, Manuel; Pancheri, Elia; Mugnai, Giacomo; Micheletti, Nicola; Tomelleri, Giampaolo; Carletti, Monica; Turri, Giulia; Marafioti, Vincenzo; Monaco, Salvatore; Bonetti, Bruno; Bovi, Paolo, The dispersion of myocardial repolarization in ischemic stroke and intracranial hemorrhage «Journal of Electrocardiology» , vol. 51 , n. 4 , 2018 , pp. 691-695

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