Pubblicazioni

Cenegermin in pediatric neurotrophic keratopathy  (2019)

Autori:
Pedrotti, Emilio; Bonetto, Jacopo; Cozzini, Tiziano; Fasolo, Adriano; Marchini, Giorgio
Titolo:
Cenegermin in pediatric neurotrophic keratopathy
Anno:
2019
Tipologia prodotto:
Articolo in Rivista
Tipologia ANVUR:
Articolo su rivista
Lingua:
Inglese
Formato:
A Stampa
Referee:
Nome rivista:
CORNEA
ISSN Rivista:
0277-3740
N° Volume:
38
Numero o Fascicolo:
11
Editore:
Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320
Intervallo pagine:
1450-1452
Parole chiave:
neurotrophic keratopathy; pediatric; corneal ulcer; corneal sensitivity; Cenegermin
Breve descrizione dei contenuti:
PURPOSE: We report a case of neurotrophic keratopathy (NK) arising after surgery for rhabdomyosarcoma of the jaw successfully treated with Cenegermin eye drops (Oxervate; Dompé Farmaceutici, Milan, Italy) in a 3-year-old boy. METHODS: At the age of 1 year, the boy underwent surgery for rhabdomyosarcoma of the jaw, followed by radiotherapy. Subsequent NK was initially treated with preservative-free artificial tears, topical combination of dexamethasone 0.1% and netilmicin 0.3% (Netildex; Sifi, Catania, Italy), and moxifloxacin 0.5% (Vigamox; Alcon, Fort Worth, TX), followed by 10 cycles of a topical eye biopolymer containing a poly-carboxymethyl glucose sulfate solution (Cacicol; Theà, Clermont-Ferrand, France) and 4 amniotic membrane transplantations. Keratopathy was recalcitrant to therapy and tissue transplant. Therapy was switched to Cenegermin eye drops 6 times daily for 8 weeks. RESULTS: Complete healing of the corneal epithelium was achieved at 3 weeks into treatment. CONCLUSIONS: Cenegermin was effective in restoring corneal integrity in this pediatric patient with NK.
Pagina Web:
https://doi.org/10.1097/ICO.0000000000002112
Id prodotto:
109963
Handle IRIS:
11562/999191
ultima modifica:
17 novembre 2022
Citazione bibliografica:
Pedrotti, Emilio; Bonetto, Jacopo; Cozzini, Tiziano; Fasolo, Adriano; Marchini, Giorgio, Cenegermin in pediatric neurotrophic keratopathy «CORNEA» , vol. 38 , n. 112019pp. 1450-1452

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo IRIS

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