Pubblicazioni

Autori:

Pedrotti, Emilio; Bonetto, Jacopo; Cozzini, Tiziano; Fasolo, Adriano; Marchini, Giorgio

Titolo:

Cenegermin in pediatric neurotrophic keratopathy

Anno:

2019

Tipologia prodotto:

Articolo in Rivista

Tipologia ANVUR:

Articolo su rivista

Lingua:

Inglese

Formato:

A Stampa

Referee:

Sì

Nome rivista:

CORNEA

ISSN Rivista:

0277-3740

N° Volume:

38

Numero o Fascicolo:

11

Editore:

Lippincott, Williams & Wilkins:530 Walnut Street:Philadelphia, PA 19106:(800)638-3030, (301)223-2300, EMAIL: orders@lww.com, INTERNET: http://www.lww.com, Fax: (301)223-2320, (301)223-2320

Intervallo pagine:

1450-1452

Parole chiave:

neurotrophic keratopathy; pediatric; corneal ulcer; corneal sensitivity; Cenegermin

Breve descrizione dei contenuti:

PURPOSE: We report a case of neurotrophic keratopathy (NK) arising after surgery for rhabdomyosarcoma of the jaw successfully treated with Cenegermin eye drops (Oxervate; Dompé Farmaceutici, Milan, Italy) in a 3-year-old boy. METHODS: At the age of 1 year, the boy underwent surgery for rhabdomyosarcoma of the jaw, followed by radiotherapy. Subsequent NK was initially treated with preservative-free artificial tears, topical combination of dexamethasone 0.1% and netilmicin 0.3% (Netildex; Sifi, Catania, Italy), and moxifloxacin 0.5% (Vigamox; Alcon, Fort Worth, TX), followed by 10 cycles of a topical eye biopolymer containing a poly-carboxymethyl glucose sulfate solution (Cacicol; Theà, Clermont-Ferrand, France) and 4 amniotic membrane transplantations. Keratopathy was recalcitrant to therapy and tissue transplant. Therapy was switched to Cenegermin eye drops 6 times daily for 8 weeks. RESULTS: Complete healing of the corneal epithelium was achieved at 3 weeks into treatment. CONCLUSIONS: Cenegermin was effective in restoring corneal integrity in this pediatric patient with NK.

Pagina Web:

https://doi.org/10.1097/ICO.0000000000002112

Id prodotto:

109963

Handle IRIS:

11562/999191

ultima modifica:

17 novembre 2022

Citazione bibliografica:

Pedrotti, Emilio; Bonetto, Jacopo; Cozzini, Tiziano; Fasolo, Adriano; Marchini, Giorgio, Cenegermin in pediatric neurotrophic keratopathy «CORNEA» , vol. 38 , n. 11 , 2019 , pp. 1450-1452

Consulta la scheda completa presente nel repository istituzionale della Ricerca di Ateneo